Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells

EE Bastounis, F Serrano-Alcalde, P Radhakrishnan… - Developmental cell, 2021 - cell.com
Intracellular pathogens alter their host cells' mechanics to promote dissemination through
tissues. Conversely, host cells may respond to the presence of pathogens by altering their …

Optimal concentration of necrostatin-1 for protecting against hippocampal neuronal damage in mice with status epilepticus

DQ Lin, XY Cai, CH Wang, B Yang… - Neural regeneration …, 2020 - journals.lww.com
Hippocampal neurons undergo various forms of cell death after status epilepticus.
Necrostatin-1 specifically inhibits necroptosis mediated by receptor interacting protein …

Modulação da resposta anti-tumoral por agentes infecciosos modificados geneticamente

A Rana - 2019 - teses.usp.br
Uma indução eficiente de células T CD8+ antígeno-específicas efetoras e de longa
duração, através de estratégias de vacinação, é essencial para eliminar células tumorais ou …