A guide to chemokines and their receptors

CE Hughes, RJB Nibbs - The FEBS journal, 2018 - Wiley Online Library
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …

Mechanisms of regulation of the chemokine-receptor network

MJ Stone, JA Hayward, C Huang, Z E. Huma… - International journal of …, 2017 - mdpi.com
The interactions of chemokines with their G protein-coupled receptors promote the migration
of leukocytes during normal immune function and as a key aspect of the inflammatory …

Staphylococcus aureus pore-forming toxins: The interface of pathogen and host complexity

ES Seilie, JB Wardenburg - Seminars in cell & developmental biology, 2017 - Elsevier
Staphylococcus aureus is a prominent human pathogen capable of infecting a variety of host
species and tissue sites. This versatility stems from the pathogen's ability to secrete diverse …

Tuning inflammation and immunity by chemokine sequestration: decoys and more

A Mantovani, R Bonecchi, M Locati - Nature Reviews Immunology, 2006 - nature.com
A set of chemokine receptors are structurally unable to elicit migration or conventional
signalling responses after ligand engagement. These'silent'(non-signalling) chemokine …

Plasmodium vivax infections of Duffy-negative erythrocytes: historically undetected or a recent adaptation?

K Gunalan, A Niangaly, MA Thera, OK Doumbo… - Trends in …, 2018 - cell.com
Plasmodium vivax is the main cause of malarial disease in Asia and South America.
Plasmodium vivax infection was thought to be absent in African populations who are Duffy …

The sweet spot: how GAGs help chemokines guide migrating cells

Y Monneau, F Arenzana-Seisdedos… - Journal of Leucocyte …, 2016 - academic.oup.com
Glycosaminoglycans are polysaccharides that occur both at the cell surface and within
extracellular matrices. Through their ability to bind to a large array of proteins, almost 500 of …

Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain

SK Singh, R Hora, H Belrhali, CE Chitnis, A Sharma - Nature, 2006 - nature.com
Molecular processes that govern pathogenic features of erythrocyte invasion and
cytoadherence in malaria are reliant on Plasmodium-specific Duffy-binding-like domains …

Fya/Fyb antigen polymorphism in human erythrocyte Duffy antigen affects susceptibility to Plasmodium vivax malaria

CL King, JH Adams, J Xianli… - Proceedings of the …, 2011 - National Acad Sciences
Plasmodium vivax (Pv) is a major cause of human malaria and is increasing in public health
importance compared with falciparum malaria. Pv is unique among human malarias in that …

Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals

C Dechavanne, S Dechavanne, J Bosch, S Metral… - Cell Host & Microbe, 2023 - cell.com
The erythrocyte silent Duffy blood group phenotype in Africans is thought to confer
resistance to Plasmodium vivax blood-stage infection. However, recent studies report P …

Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins

MJ Stone, S Chuang, X Hou, M Shoham, JZ Zhu - New biotechnology, 2009 - Elsevier
The post-translational sulfation of tyrosine residues occurs in numerous secreted and
integral membrane proteins and, in many cases, plays a crucial role in controlling the …