Scarless wound healing: current insights from the perspectives of TGF-β, KGF-1, and KGF-2

W Xiaojie, J Banda, H Qi, AK Chang, C Bwalya… - Cytokine & growth factor …, 2022 - Elsevier
The process of wound healing involves a complex and vast interplay of growth factors and
cytokines that coordinate the recruitment and interaction of various cell types. A series of …

Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway

NC Sondermann, S Faßbender, F Hartung… - Biochemical …, 2023 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …

[HTML][HTML] Aryl hydrocarbon receptor activation modulates intestinal epithelial barrier function by maintaining tight junction integrity

M Yu, Q Wang, Y Ma, L Li, K Yu, Z Zhang… - … journal of biological …, 2018 - ncbi.nlm.nih.gov
Activation of Aryl hydrocarbon receptor (AhR) is involved in the control of intestinal mucosal
homeostasis. Intestinal barrier dysfunction contributes to the development of many intestinal …

Activation of proinflammatory responses in cells of the airway mucosa by particulate matter: oxidant-and non-oxidant-mediated triggering mechanisms

J Øvrevik, M Refsnes, M Låg, JA Holme, PE Schwarze - Biomolecules, 2015 - mdpi.com
Inflammation is considered to play a central role in a diverse range of disease outcomes
associated with exposure to various types of inhalable particulates. The initial mechanisms …

Genome-wide analysis of DNA methylation and fine particulate matter air pollution in three study populations: KORA F3, KORA F4, and the normative aging study

T Panni, AJ Mehta, JD Schwartz… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: Epidemiological studies have reported associations between particulate matter
(PM) concentrations and cancer and respiratory and cardiovascular diseases. DNA …

[HTML][HTML] Lung cancer associated with combustion particles and fine particulate matter (PM2. 5)-The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl …

JA Holme, J Vondráček, M Machala… - Biochemical …, 2023 - Elsevier
Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

Genomic predictors of asthma phenotypes and treatment response

N Hernandez-Pacheco, M Pino-Yanes… - Frontiers in …, 2019 - frontiersin.org
Asthma is a complex respiratory disease considered as the most common chronic condition
in children. A large genetic contribution to asthma susceptibility is predicted by the clustering …

[HTML][HTML] Per-and polyfluoroalkyl substances (PFASs) modify lung surfactant function and pro-inflammatory responses in human bronchial epithelial cells

JB Sørli, M Låg, L Ekeren, J Perez-Gil, LS Haug… - Toxicology in Vitro, 2020 - Elsevier
The toxicity of some per-and polyfluoroalkyl substances (PFASs), such as perfluorooctane
sulfonate (PFOS) and perfluorooctanoic acid (PFOA) has been studied thoroughly, showing …

Regulation of differentiation and generation of osteoclasts in rheumatoid arthritis

Q Niu, J Gao, L Wang, J Liu, L Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Introduction Rheumatoid arthritis (RA), which affects nearly 1% of the world's population, is a
debilitating autoimmune disease. Bone erosion caused by periarticular osteopenia and …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …