Pericytes are mural vascular cells covering microvascular capillaries, where they contribute
to the formation, maturation, maintenance, stabilisation and remodelling of vasculature. They …

Vascular diseases are the underlying pathology in many life-threatening illnesses. Human
cellular and molecular mechanisms involved in angiogenesis are complex and difficult to …

Chemokine receptor CXCR4 plays a crucial role in leukocyte recruitment and inflammation
regulation to influence tissue repair in ischemic diseases. Here we assessed the effect of …

The generation of endothelial cells (ECs) from human pluripotent stem cells (PSCs) has
been a promising approach for treating cardiovascular diseases for several years. Human …

Coronavirus disease (COVID-19) causes various vascular and blood-related reactions,
including exacerbated responses. The role of endothelial cells in this acute response is …

Autologous photoreceptor cell replacement is one of the most promising approaches
currently under development for the treatment of inherited retinal degenerative blindness …

Vascular pathologies are prevalent in a broad spectrum of diseases, necessitating a deeper
understanding of vascular biology, particularly in overcoming the oxygen and nutrient …

Pericytes (PCs) are versatile cells integral to the microcirculation wall, exhibiting specific
stem cell traits. They are essential in modulating blood flow, ensuring vascular permeability …

The human retina is a complex tissue within the human eye and essential for the sense of
sight. Retinal diseases, such as age-related macular degeneration (AMD) or retinitis …

Development of patient-derived induced pluripotent stem cells, next-generation sequencing
and genome editing technologies have fueled the field of personalized medicine, which can …