Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders

WS Blaner - Pharmacology & therapeutics, 2019 - Elsevier
Much evidence has accumulated in the literature over the last fifteen years that indicates
vitamin A has a role in metabolic disease prevention and causation. This literature proposes …

Mechanistic aspects of carotenoid health benefits–where are we now?

T Bohn, ML Bonet, P Borel, J Keijer… - Nutrition Research …, 2021 - cambridge.org
Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

W Sun, H Dong, M Balaz, M Slyper, E Drokhlyansky… - Nature, 2020 - nature.com
Adipose tissue is usually classified on the basis of its function as white, brown or beige
(brite). It is an important regulator of systemic metabolism, as shown by the fact that …

High fat/high glucose diet induces metabolic syndrome in an experimental rat model

S Moreno-Fernández, M Garcés-Rimón, G Vera… - Nutrients, 2018 - mdpi.com
Metabolic syndrome (MetS) is defined as a constellation of many metabolic disorders such
as hypertension, impaired glucose tolerance, dyslipidemia and obesity, being this last …

Anti-obesity effect of carotenoids: direct impact on adipose tissue and adipose tissue-driven indirect effects

L Mounien, F Tourniaire, JF Landrier - Nutrients, 2019 - mdpi.com
This review summarizes current knowledge on the biological relevance of carotenoids and
some of their metabolites in obesity management. The relationship between carotenoids …

[HTML][HTML] Dietary factors promoting brown and beige fat development and thermogenesis

M Okla, J Kim, K Koehler, S Chung - Advances in nutrition, 2017 - Elsevier
Brown adipose tissue (BAT) is a specialized fat tissue that has a high capacity to dissociate
cellular respiration from ATP utilization, resulting in the release of stored energy as heat …

β-Carotene in the human body: metabolic bioactivation pathways–from digestion to tissue distribution and excretion

T Bohn, C Desmarchelier, SN El, J Keijer… - Proceedings of the …, 2019 - cambridge.org
β-Carotene intake and tissue/blood concentrations have been associated with reduced
incidence of several chronic diseases. Further bioactive carotenoid-metabolites can …

The relationship between vitamin A status and oxidative stress in animal production

Y Shastak, A Gordillo, W Pelletier - Journal of Applied Animal …, 2023 - Taylor & Francis
Oxidative stress is caused by an imbalance between the production of harmful oxygen
molecules and the body's ability to repair their detrimental implications, leading to reduced …

Beiging of white adipose tissue as a therapeutic strategy for weight loss in humans

B Thyagarajan, MT Foster - Hormone molecular biology and clinical …, 2017 - degruyter.com
An imbalance between energy intake and expenditure leads to obesity. Adiposity associated
with obesity progressively causes inflammation, type 2 diabetes, hypertension …

Lycopene and tomato powder supplementation similarly inhibit high‐fat diet induced obesity, inflammatory response, and associated metabolic disorders

S Fenni, H Hammou, J Astier, L Bonnet… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Several studies have linked the high intake of lycopene or tomatoes products with
lower risk for metabolic diseases. The aim of the present study was to evaluate and to …