[HTML][HTML] Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI
Oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO 2) are
key cerebral physiological parameters to identify at-risk cerebrovascular patients and …
key cerebral physiological parameters to identify at-risk cerebrovascular patients and …
Non-invasive kinetic modelling approaches for quantitative analysis of brain PET studies
CWJ Van Der Weijden, P Mossel, AL Bartels… - European Journal of …, 2023 - Springer
Pharmacokinetic modelling with arterial sampling is the gold standard for analysing dynamic
PET data of the brain. However, the invasive character of arterial sampling prevents its …
PET data of the brain. However, the invasive character of arterial sampling prevents its …
Cerebral blood flow measurements with 15O-water PET using a non-invasive machine-learning-derived arterial input function
Cerebral blood flow (CBF) can be measured with dynamic positron emission tomography
(PET) of 15O-labeled water by using tracer kinetic modelling. However, for quantification of …
(PET) of 15O-labeled water by using tracer kinetic modelling. However, for quantification of …
Image-derived input functions from dynamic 15O–water PET scans using penalised reconstruction
P Young, L Appel, A Tolf, S Kosmidis, J Burman… - EJNMMI physics, 2023 - Springer
Background Quantitative positron emission tomography (PET) scans of the brain typically
require arterial blood sampling but this is complicated and logistically challenging. One …
require arterial blood sampling but this is complicated and logistically challenging. One …
Promise of fully integrated PET/MRI: noninvasive clinical quantification of cerebral glucose metabolism
We describe a fully automated processing pipeline to support the noninvasive absolute
quantification of the cerebral metabolic rate for glucose (CMRGlc) in a clinical setting. This …
quantification of the cerebral metabolic rate for glucose (CMRGlc) in a clinical setting. This …
Multimodal analysis using [11C]PiB-PET/MRI for functional evaluation of patients with Alzheimer's disease
Abstract Background Multimodal PET/MRI image data simultaneously obtained from patients
with early-stage of Alzheimer's disease (eAD) were assessed in order to observe …
with early-stage of Alzheimer's disease (eAD) were assessed in order to observe …
Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation
H Okazawa, Y Higashino, T Tsujikawa… - European Journal of …, 2018 - Elsevier
Purpose A noninvasive image derived input function (IDIF) method was applied to estimate
arterial input function from brain H 2 15 O-PET/MRI images for the measurement of cerebral …
arterial input function from brain H 2 15 O-PET/MRI images for the measurement of cerebral …
[HTML][HTML] Investigation of image-derived input functions for non-invasive quantification of myelin density using [11C] MeDAS PET
CWJ van der Weijden, A van der Hoorn, Y Wang… - Neuroimage, 2022 - Elsevier
Multiple sclerosis (MS) is an inflammatory demyelinating disease. Current treatments are
focussed on immune suppression to modulate pathogenic activity that causes myelin …
focussed on immune suppression to modulate pathogenic activity that causes myelin …
Human non-REM sleep and the mean global BOLD signal
A hallmark of non-rapid eye movement (REM) sleep is the decreased brain activity as
measured by global reductions in cerebral blood flow, oxygen metabolism, and glucose …
measured by global reductions in cerebral blood flow, oxygen metabolism, and glucose …
Simultaneous PET-MRI imaging of cerebral blood flow and glucose metabolism in the symptomatic unilateral internal carotid artery/middle cerebral artery steno …
B Cui, T Zhang, Y Ma, Z Chen, J Ma, L Ma… - European Journal of …, 2020 - Springer
Purpose Cerebral blood flow (CBF) and glucose metabolism are important and significant
factors in ischaemic cerebrovascular disease. The objective of this study was to use …
factors in ischaemic cerebrovascular disease. The objective of this study was to use …