Decellularized extracellular matrix scaffolds for cardiovascular tissue engineering: current techniques and challenges

GI Barbulescu, FM Bojin, VL Ordodi, ID Goje… - International journal of …, 2022 - mdpi.com
Cardiovascular diseases are the leading cause of global mortality. Over the past two
decades, researchers have tried to provide novel solutions for end-stage heart failure to …

Cardiac tissue-derived extracellular matrix scaffolds for myocardial repair: advantages and challenges

P Kc, Y Hong, G Zhang - Regenerative biomaterials, 2019 - academic.oup.com
Decellularized extracellular matrix (dECM) derived from myocardium has been widely
explored as a nature scaffold for cardiac tissue engineering applications. Cardiac dECM …

Extracellular matrix–based biomaterials for cardiac regeneration and repair

H Li, M Bao, Y Nie - Heart failure reviews, 2021 - Springer
The spectrum of ischemic heart diseases, encompassing acute myocardial infarction to heart
failure, represents the leading cause of death worldwide. Although extensive progress in …

Whole-heart tissue engineering and cardiac patches: challenges and promises

A Akbarzadeh, S Sobhani, A Soltani Khaboushan… - Bioengineering, 2023 - mdpi.com
Despite all the advances in preventing, diagnosing, and treating cardiovascular disorders,
they still account for a significant part of mortality and morbidity worldwide. The advent of …

Novel approaches toward the generation of bioscaffolds as a potential therapy in cardiovascular tissue engineering

F Shahabipour, M Banach, TP Johnston, M Pirro… - International journal of …, 2017 - Elsevier
Cardiovascular disease associated with myocardial infarction (MI) is among the leading
causes of mortality worldwide, in part, due to the limited regenerative capacity of tissues …

Cardiac extracellular matrix modification as a therapeutic approach

ML Hall, BM Ogle - Cardiac Extracellular Matrix: Fundamental Science to …, 2018 - Springer
The cardiac extracellular matrix (cECM) is comprised of proteins and polysaccharides
secreted by cardiac cell types, which provide structural and biochemical support to …

Modeling the human heart ex vivo—current possibilities and strive for future applications

E Kałużna, A Nadel, A Zimna… - Journal of Tissue …, 2022 - Wiley Online Library
The high organ specification of the human heart is inversely proportional to its functional
recovery after damage. The discovery of induced pluripotent stem cell‐derived …

Translational applications of tissue engineering in cardiovascular medicine

A Dogan, A Eser Elcin… - Current pharmaceutical …, 2017 - ingentaconnect.com
Cardiovascular diseases are the leading cause of global deaths. The current paradigm in
medicine seeks novel approaches for the treatment of progressive or end-stage diseases …

Optimal environmental stiffness for stem cell mediated ischemic myocardium repair

H Liu, C Paul, M Xu - Adult Stem Cells: Methods and Protocols, 2017 - Springer
Cardiovascular diseases related to myocardial infarction (MI) contribute significantly to
morbidity and mortality worldwide. The loss of cardiomyocytes during MI is a key factor in the …

Current trends in biomaterial utilization for cardiopulmonary system regeneration

AOJ Fakoya, DA Otohinoyi, J Yusuf - Stem Cells International, 2018 - Wiley Online Library
The cardiopulmonary system is made up of the heart and the lungs, with the core function of
one complementing the other. The unimpeded and optimal cycling of blood between these …