Current progress in sports genomics

II Ahmetov, ON Fedotovskaya - Advances in clinical chemistry, 2015 - Elsevier
Understanding the genetic architecture of athletic performance is an important step in the
development of methods for talent identification in sport. Research concerned with …

Markers of response for the antiangiogenic agent bevacizumab

D Lambrechts, HJ Lenz, S de Haas… - Journal of Clinical …, 2013 - ascopubs.org
Bevacizumab is the first antiangiogenic therapy proven to slow metastatic disease
progression in patients with cancer. Although it has changed clinical practice, some patients …

The vascular endothelial growth factor family in adverse pregnancy outcomes

PH Andraweera, GA Dekker… - Human reproduction …, 2012 - academic.oup.com
BACKGROUND Pre-eclampsia, small-for-gestational-age infants, preterm birth and
recurrent miscarriage complicate a significant number of pregnancies. The vascular …

Bevacizumab-induced hypertension: Clinical presentation and molecular understanding

M Li, DL Kroetz - Pharmacology & therapeutics, 2018 - Elsevier
Bevacizumab is a vascular endothelial growth factor-A-specific angiogenesis inhibitor
indicated as an adjunct to chemotherapy for the treatment of several types of cancer …

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity

NP van Erp, K Eechoute, AA van der Veldt… - Journal of Clinical …, 2009 - ascopubs.org
Purpose To identify genetic markers in the pharmacokinetic and pharmacodynamic
pathways of sunitinib that predispose for development of toxicities: thrombocytopenia …

Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes

CF Xu, NX Bing, HA Ball, D Rajagopalan… - Journal of clinical …, 2011 - ascopubs.org
Purpose Pazopanib, an oral angiogenesis inhibitor, is approved for the treatment of
advanced renal cell carcinoma (RCC). Response to pazopanib monotherapy varies …

Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

CBM Platania, L Di Paola, GM Leggio… - Frontiers in …, 2015 - frontiersin.org
Anti-angiogenic agents are biological drugs used for treatment of retinal neovascular
degenerative diseases. In this study, we aimed at in silico analysis of interaction of vascular …

Comparative genomic analysis of primary and synchronous metastatic colorectal cancers

SY Lee, F Haq, D Kim, C Jun, HJ Jo, SM Ahn, WS Lee - PloS one, 2014 - journals.plos.org
Approximately 50% of patients with primary colorectal carcinoma develop liver metastases.
Understanding the genetic differences between primary colon cancer and their metastases …

Gene polymorphisms and fiber-type composition of human skeletal muscle

II Ahmetov, OL Vinogradova… - … journal of sport …, 2012 - journals.humankinetics.com
The ability to perform aerobic or anaerobic exercise varies widely among individuals,
partially depending on their muscle-fiber composition. Variability in the proportion of skeletal …

Placental expression of VEGF family mRNA in adverse pregnancy outcomes

PH Andraweera, GA Dekker, JA Laurence, CT Roberts - Placenta, 2012 - Elsevier
INTRODUCTION: The pregnancy complications preeclampsia, gestational hypertension,
small for gestational age infants (SGA) and pre-term birth (PTB) affect approximately 21% of …