Exposure to organophosphates in association with the development of insulin resistance: Evidence from in vitro, in vivo, and clinical studies

M Seesen, W Pratchayasakul, H Pintana… - Food and Chemical …, 2022 - Elsevier
Insulin resistance is an underlying condition prior to the development of several diseases,
including type 2 diabetes, cardiovascular diseases, cognitive impairment, and …

Testicular toxicity of cisplatin in rats: ameliorative effect of lycopene and N-acetylcysteine

A Elsayed, A Elkomy, M Alkafafy, R Elkammar… - … Science and Pollution …, 2022 - Springer
Lycopene (LP) and N-acetylcysteine (NAC) protective effects were assessed for testicular
toxicity mediated by cisplatin (CP) in rats. Forty-nine rats were divided into 7 groups (n= 7); …

Antioxidant effects of N‐acetylcysteine on the male reproductive system: A systematic review

A Ghafarizadeh, M Malmir, S Naderi Noreini… - Andrologia, 2021 - Wiley Online Library
This study aimed to evaluate the effect of N‐acetyl cysteine on the male reproductive system
and consensus and classification of data found from previous studies. It is undeniable that N …

Cu-induced spermatogenesis disease is related to oxidative stress-mediated germ cell apoptosis and DNA damage

H Guo, Y Ouyang, J Wang, H Cui, H Deng… - Journal of Hazardous …, 2021 - Elsevier
Copper is considered as an indispensable trace element for living organisms. However,
over-exposure to Cu can lead to adverse health effects on human. In this study, CuSO 4 …

[HTML][HTML] Oxidative stress-mediated apoptosis and autophagy involved in Ni-induced nephrotoxicity in the mice

H Guo, H Yin, Z Zuo, Z Yang, Y Yang, L Wei… - Ecotoxicology and …, 2021 - Elsevier
As an extensively environmental pollution, Nickel (Ni) represents a serious hazard to human
health. The present study focused on exploring the mechanism of Ni-mediated …

PIN1-mediated ROS production is involved in antagonism of N-acetyl-L-cysteine against arsenic-induced hepatotoxicity

H Zhang, Z He, P Deng, M Lu, C Zhou… - Toxicology …, 2022 - academic.oup.com
Arsenic, a widely existing environmental contaminant, is recognized to be toxic to multiple
organs. Exposure to arsenic results in liver damage via excessive production of reactive …

N‐acetyl cysteine co‐treatment abates perfluorooctanoic acid‐induced reproductive toxicity in male rats

SE Owumi, AP Akomolafe, IO Imosemi… - Andrologia, 2021 - Wiley Online Library
Perfluorooctanoic acid is a synthetic perfluoroalkyl—persistent in the environment and toxic
to humans. N‐acetylcysteine is a pro‐drug of both amino acid l‐cysteine and glutathione—a …

Differentiation of neonate mouse spermatogonia on two-dimensional and three-dimensional culture systems supplemented with d-serine and dizocilpine (mk-801)

AE Noghani, R Asadpour, A Saberivand, Z Mazaheri… - Theriogenology, 2022 - Elsevier
Abstract N-methyl-d-aspartate (NMDA) modulates the spermatogenesis process through
stimulating the steroid hormone biosynthesis. The aim of this study was to evaluate the …

Nickel induces epithelial‐mesenchymal transition in pulmonary fibrosis in mice via activation of the oxidative stress‐mediated TGF‐β1/Smad signaling pathway

S Cao, H Yin, X Li, X Zeng, J Liu - Environmental Toxicology, 2024 - Wiley Online Library
Nickel (Ni) is recognized as a carcinogenic metal, and its widespread use has led to severe
environmental and health problems. Although the lung is among the main organs affected …

Effect of nmda receptor agonist and antagonist on spermatogonial stem cells proliferation in 2-and 3-dimensional culture systems

AE Noghani, R Asadpour, A Saberivand… - Molecular Biology …, 2022 - Springer
Background The main purpose of this study was to investigate the effect of D-serine (DS)
and Dizocilpine (MK-801) on the proliferation of spermatogonial stem cells (SSCs) in two …