Recent work with approaches like recombinant mutants and X-ray crystallography has given
much new information about the ligand-binding properties of human serum albumin (HSA) …

The binding of drugs to plasma proteins, such as albumin and a1-acid glycoprotein (AGP) is
a major determinant in the disposition of drugs. A topology analysis of drug binding sites on …

The interaction between four flavonoids (catechin, epicatechin, rutin, and quercetin) and
bovine serum albumin (BSA) was investigated using tryptophan fluorescence quenching …

Background The majority of surgical patients receive inhaled anesthetics, principally small
haloalkanes and haloethers. Long-term cognitive problems occur in the elderly subsequent …

Flavonoids, a group of naturally occurring antioxidants and metal chelators, can be used as
tyrosinase inhibitors due to their formation of copper− flavonoid complexes. Thus, to …

Quercetin (3, 3′, 4′, 5, 7-pentahydroxyflavone), a ubiquitous, bioactive plant flavonoid, is
known to possess anti-cancer, anti-tumor, and other important therapeutic activities of …

Human serum albumin (HSA) exists in both reduced and oxidized forms, and the percentage
of oxidized albumin increases in several diseases. However, little is known regarding the …

Background Human serum albumin is the principal protein in human serum. It participates in
regulation of plasma oncotic pressure and transports endogenous and exogenous ligands …

Puerarin is a widely used compound in Chinese traditional medicine and exhibits many
pharmacological activities. Binding of puerarin to human serum albumin (HSA) was …

Quercetin is an important dietary flavonoid with in vitro antioxidant activity. However, it is
found in human plasma as conjugates with glucuronic acid, sulfate or methyl groups, with no …