Chalcone synthesis, properties and medicinal applications: a review

A Rammohan, JS Reddy, G Sravya, CN Rao… - Environmental …, 2020 - Springer
Chalcone is an aromatic ketone that forms the central core of many important biological
compounds, which are known as chalcones. Chalcones are the biogenetic precursors of …

Arylglyoxals in synthesis of heterocyclic compounds

B Eftekhari-Sis, M Zirak, A Akbari - Chemical reviews, 2013 - ACS Publications
Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

Recent advancements in the development of bioactive pyrazoline derivatives

B Nehra, S Rulhania, S Jaswal, B Kumar… - European journal of …, 2020 - Elsevier
Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

Solvent-free heterocyclic synthesis

MAP Martins, CP Frizzo, DN Moreira, L Buriol… - Chemical …, 2009 - ACS Publications
Heterocycles form, by far, the largest of the classical divisions of organic chemistry.
Moreover, they are of immense importance not only biologically and industrially but also to …

Antimicrobial, antioxidant, and anticancer activities of some novel isoxazole ring containing chalcone and dihydropyrazole derivatives

A Shaik, RR Bhandare, K Palleapati, S Nissankararao… - Molecules, 2020 - mdpi.com
Our previous work identified isoxazole-based chalcones and their dihydropyrazole
derivatives as two important five-membered heterocycles having antitubercular activity …

Total synthesis of natural products containing benzofuran rings

MM Heravi, V Zadsirjan, H Hamidi, PHT Amiri - RSC advances, 2017 - pubs.rsc.org
Research on natural products containing benzofuran has remarkably increased during the
past few decades. Newly isolated natural products with complex structures are being …

[PDF][PDF] Pyrazoline derivatives: a worthy insight into the recent advances and potential pharmacological activities

MA Rahman, AA Siddiqui - Int J Pharm Sci Drug Res, 2010 - researchgate.net
Pyrazolines display a broad spectrum of potential pharmacological activities and are present
in a number of pharmacologically active molecules such as phenazone/amidopyrene …

Clean grinding technique: A facile synthesis and in silico antiviral activity of hydrazones, pyrazoles, and pyrazines bearing thiazole moiety against SARS-CoV-2 main …

S Abu-Melha, MM Edrees, SM Riyadh, MR Abdelaziz… - Molecules, 2020 - mdpi.com
A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop
grinding of thiazole carbohydrazide 2 with various carbonyl compounds. Also, dehydrative …

Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity

DS Reddy, M Kongot, A Kumar - Tuberculosis, 2021 - Elsevier
Tuberculosis (TB) is a highly contagious airborne disease with nearly 25% of the world's
population infected with it. Challenges such as multi drug resistant TB (MDR-TB), extensive …

Recurrent π–π stacking motifs in three new 4, 5-dihydropyrazolyl–thiazole–coumarin hybrids: X-ray characterization, Hirshfeld surface analysis and DFT calculations

M Madni, MN Ahmed, M Hafeez, M Ashfaq… - New Journal of …, 2020 - pubs.rsc.org
The synthesis and X-ray characterization of three new 4, 5-dihydropyrazolylthiazole–
coumarin hybrids (1–3) are reported herein, namely 3-(2-(3, 5-bis (4-chlorophenyl)-4, 5 …