There is an increasing amount of evidence that biomolecular condensates are linked to
neurodegenerative diseases associated with protein aggregation, such as Alzheimer's …

The intracellular environment represents an extremely crowded milieu, with a limited amount
of free water and an almost complete lack of unoccupied space. Obviously, slightly salted …

Proteins are the major component of the living cell. They play crucial roles in the
maintenance of life, and their dysfunctions are known to cause different pathologies. One of …

Macromolecular crowding is known to affect protein folding, binding of small molecules,
interaction with nucleic acids, enzymatic activity, protein-protein interactions, and protein …

The agricultural and food industry sectors play essential roles in the global economy, but
also generate significant amounts of wastes every year associated to their activities, which …

It is now generally accepted that macromolecules do not act in isolation but “live” in a
crowded environment, that is, an environment populated by numerous different molecules …

Since the inception of the human microbiome project (HMP) by the US National Institutes of
Health (NIH) in 2007 there has been a keen resurgence in our recognition of the human …

Protein pharmaceuticals have become a significant class of marketed drug products and are
expected to grow steadily over the next decade. Development of a commercial protein …

Living cells contain numerous subcellular compartments, many of which lack membranous
boundaries and are thought to occur due to liquid–liquid phase coexistence. This review will …

Background The environment inside cells in which proteins fold and function are quite
different from that of the dilute buffer solutions often used during in vitro experiments. The …