Isatin and its derivatives: a survey of recent syntheses, reactions, and applications

R Kakkar - MedChemComm, 2019 - pubs.rsc.org
Isatin (1H-indole-2, 3-dione) and its derivatives represent an important class of heterocyclic
compounds that can be used as precursors for drug synthesis. Since its discovery, a lot of …

The applications of dimethyl sulfoxide as reagent in organic synthesis

XF Wu, K Natte - Advanced Synthesis & Catalysis, 2016 - Wiley Online Library
Dimethyl sulfoxide (DMSO) is one of the most commonly applied organic solvents in
chemical transformations and is utilized widely in industrial processes as well. During the …

Metal‐free cross‐dehydrogenative coupling (CDC): molecular iodine as a versatile catalyst/reagent for CDC reactions

PT Parvatkar, R Manetsch… - Chemistry–An Asian …, 2019 - Wiley Online Library
The development of ecofriendly methods for carbon–carbon (C− C) and carbon–heteroatom
(C− Het) bond formation is of great significance in modern‐day research. Metal‐free cross …

Electrohalogenation of organic compounds

MR Scheide, CR Nicoleti, GM Martins… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Herein, we present an overview of recent advances in the electrochemical halogenation of
organic compounds. Halogen-containing compounds are essential building blocks for post …

AC= O⋅⋅⋅ Isothiouronium Interaction Dictates Enantiodiscrimination in Acylative Kinetic Resolutions of Tertiary Heterocyclic Alcohols

MD Greenhalgh, SM Smith, DM Walden… - Angewandte …, 2018 - Wiley Online Library
A combination of experimental and computational studies have identified a C= O⋅⋅⋅
isothiouronium interaction as key to efficient enantiodiscrimination in the kinetic resolution of …

Electrocatalytic C–H/N–H coupling of 2′-aminoacetophenones for the synthesis of isatins

P Qian, JH Su, Y Wang, M Bi, Z Zha… - The Journal of Organic …, 2017 - ACS Publications
2′-Aminoacetophenones undergo a C (sp3)–H oxidation followed by intramolecular C–N
bond formation by virtue of a simple electrochemical oxidation in the presence of n-Bu4NI …

Iodine/DMSO oxidations: a contemporary paradigm in C–N bond chemistry

A Monga, S Bagchi, A Sharma - New Journal of Chemistry, 2018 - pubs.rsc.org
A new era in the organic synthetic world is demanding greener protocols for the execution of
reactions. As the world is progressing towards fewer natural resources and high energy …

I2‐Catalyzed Cycloisomerization of Ynamides: Chemoselective and Divergent Access to Indole Derivatives

BH Zhu, SB Ye, ML Nie, ZY Xie, YB Wang… - Angewandte …, 2023 - Wiley Online Library
Herein, an I2‐catalyzed unprecedented cycloisomerization of ynamides is developed,
furnishing various functionalized bis (indole) derivatives in generally good to excellent yields …

Synthesis of Luminescent Indolo[2,1-b]quinazolin-6(12H)-ones via a Sequential Ugi/Iodine-Promoted Cyclization/Staudinger/Aza-Wittig Reaction

ML Yang, L Zhao, HR Chen… - The Journal of Organic …, 2023 - ACS Publications
A new efficient synthesis of indolo [2, 1-b] quinazolin-6 (12 H)-ones via a sequential
Ugi/iodine-promoted cyclization/Staudinger/aza-Wittig reaction was developed. The acid …

K 2 S 2 O 8-mediated metal-free direct C–H functionalization of quinones using arylboronic acids

A Ilangovan, A Polu, G Satish - Organic Chemistry Frontiers, 2015 - pubs.rsc.org
Direct C–H functionalization of quinones with arylboronic acids is achieved using K2S2O8
as the sole and efficient green catalytic system. This method provides a straightforward and …