Due to the biological complexity of the cardiovascular system, the animal model is an urgent
pre-clinical need to advance our knowledge of cardiovascular disease and to explore new …

The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy
is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic …

Recent data on Duchenne muscular dystrophy (DMD) show myocyte progenitor's
involvement in the disease pathology often leading to the DMD patient's death. The …

In 2002 we published an article describing a population of vessel-associated progenitors
that we termed mesoangioblasts (MABs). During the past decade evidence had …

Duchenne muscular dystrophy is a highly progressive muscle wasting disease of early
childhood and characterized by complex pathophysiological and histopathological changes …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy. DMD
patients lack dystrophin protein and develop skeletal muscle pathology and dilated …

Noncoding RNAs (ncRNAs) such as miRNAs and long noncoding RNAs modulate gene
transcription in response to environmental stressors and other stimuli. A role for ncRNAs in …

To be clinically relevant as a therapy for heart failure, endogenous progenitor cells must be
isolated and expanded from aged and/or diseased tissue. Here, we investigated the effect of …

Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), and X-linked
dilated cardiomyopathy (XL-DCM) consist of a unique clinical entity, the dystrophinopathies …

Nestin+ cardiac stem cells differentiate into striated cells following myocardial infarct.
Transplantation of exogenous stem cells into myocardium of a murine model for Duchenne …