The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Polymer prodrugs are based on the covalent linkage of therapeutic molecules to a polymer
structure which avoids the problems and limitations commonly encountered with traditional …

Multi-telechelic polyethylene glycol (PEG)-based multimers with multiple reactive groups at
both ends of the molecular chains can be used to prepare solid–solid phase change …

The development of facile and efficient polymerizations toward functional polymers with
unique structures and attractive properties is of great academic and industrial significance …

Drug–polymer conjugates that can self-assemble into nanoparticles are promising drug
delivery systems that improve the drug bioavailability and allow their controlled release …

Nanoparticles may provide a viable way for neuroprotective drugs to cross the blood–brain
barrier (BBB), which limits the passage of most drugs from the peripheral circulation to the …

The copolymers of acrylonitrile and acrylic acid are synthesized for the first time by
trithiocarbonate-mediated reversible addition-fragmentation chain transfer polymerization in …

Well-defined, heterotelechelic polymer prodrugs for combination therapy were synthesized
by using a combination of the “drug-initiated” nitroxide-mediated polymerization from a …

Using the easily accessible 2-azaallyl anions as initiators, the one-pot synthesis of well-
defined primary amine-ended telechelic polyaziridines (α-NH2 PAzs) has been achieved …

A facile and general synthetic methodology has been developed to prepare high drug
loading heterotelechelic polymer prodrug nanoparticles; that are nanoparticles obtained by …