Tumor metabolic regulators: key drivers of metabolic reprogramming and the promising targets in cancer therapy
K Huang, Y Han, Y Chen, H Shen, S Zeng, C Cai - Molecular Cancer, 2025 - Springer
Metabolic reprogramming within the tumor microenvironment (TME) is a hallmark of cancer
and a crucial determinant of tumor progression. Research indicates that various metabolic …
and a crucial determinant of tumor progression. Research indicates that various metabolic …
Therapeutic potential of arginine deprivation therapy for gliomas: A systematic review of the existing literature
C Yuxiao, W Jiachen, L Yanjie, L Shenglan… - Frontiers in …, 2024 - frontiersin.org
Background Arginine deprivation therapy (ADT) hinders glioma cells' access to nutrients by
reducing peripheral blood arginine, showing great efficacy in various studies, which …
reducing peripheral blood arginine, showing great efficacy in various studies, which …
Metabolic regulation in normal and leukemic stem cells
Hematopoietic stem cells (HSCs) and leukemic stem cells (LSCs) are crucial for ensuring
hematopoietic homeostasis and driving leukemia progression, respectively. Recent …
hematopoietic homeostasis and driving leukemia progression, respectively. Recent …
[HTML][HTML] Unlocking the Heterogeneity in Acute Leukaemia: Dissection of Clonal Architecture and Metabolic Properties for Clinical Interventions
MM Capelletti, O Montini, E Ruini, S Tettamanti… - International Journal of …, 2024 - mdpi.com
Genetic studies of haematological cancers have pointed out the heterogeneity of leukaemia
in its different subpopulations, with distinct mutations and characteristics, impacting the …
in its different subpopulations, with distinct mutations and characteristics, impacting the …