Wounds are considered to be a serious problem that affects the healthcare sector in many
countries, primarily due to diabetes and obesity. Wounds become worse because of …

Background Flavonoids are a class of compounds with a wide variety of biological functions,
being an important source of new products with pharmaceutical potential, including …

Ethnopharmacological relevance The human skin constitutes a biological barrier against
external stress and wounds can reduce the role of its physiological structure. In medical …

Diabetes mellitus (type 1 and type 2) and its various complications continue to place a huge
burden on global medical resources, despite the availability of numerous drugs that …

Honey is a natural ready-to-eat product rich in flavonoids, which is known by the wound
healing properties due to both antibacterial and antioxidant activity. Flavonoids mitigate …

Repairing the wound is a multistep process that includes the spatial and temporal
synchronization of a different range of cell types to increase the speed of wound contraction …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

Crocus sativus L. has been cultivated throughout history to obtain its flowers, whose dried
stigmas give rise to the spice known as saffron. Crocetin esters, picrocrocin, and safranal are …

The prevalence of type 2 diabetes mellitus (T2DM) is increasing every year. Medications are
currently the most common therapy for T2DM. However, these medications have certain …

Featured Application This manuscript seeks an extensive and comprehensive review of the
literature on the complexity of chronic wounds, highlighting therapeutic wound dressings …