Current hurdles to the translation of nanomedicines from bench to the clinic

S Đorđević, MM Gonzalez, I Conejos-Sánchez… - Drug delivery and …, 2022 - Springer
The field of nanomedicine has significantly influenced research areas such as drug delivery,
diagnostics, theranostics, and regenerative medicine; however, the further development of …

Current strategies in assessment of nanotoxicity: alternatives to in vivo animal testing

HJ Huang, YH Lee, YH Hsu, CT Liao, YF Lin… - International journal of …, 2021 - mdpi.com
Millions of experimental animals are widely used in the assessment of toxicological or
biological effects of manufactured nanomaterials in medical technology. However, the …

[HTML][HTML] Nano-QSAR modeling for predicting the cytotoxicity of metallic and metal oxide nanoparticles: A review

J Li, C Wang, L Yue, F Chen, X Cao, Z Wang - … and Environmental Safety, 2022 - Elsevier
Given the rapid development of nanotechnology, it is crucial to understand the effects of
nanoparticles on living organisms. However, it is laborious to perform toxicological tests on a …

Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine

JA Damasco, S Ravi, JD Perez, DE Hagaman… - Nanomaterials, 2020 - mdpi.com
Nanomedicine is a rapidly growing field that uses nanomaterials for the diagnosis, treatment
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …

[HTML][HTML] Using Machine Learning to make nanomaterials sustainable

JJ Scott-Fordsmand, MJB Amorim - Science of The Total Environment, 2023 - Elsevier
Sustainable development is a key challenge for contemporary human societies; failure to
achieve sustainability could threaten human survival. In this review article, we illustrate how …

A machine learning tool to predict the antibacterial capacity of nanoparticles

M Mirzaei, I Furxhi, F Murphy, M Mullins - Nanomaterials, 2021 - mdpi.com
The emergence and rapid spread of multidrug-resistant bacteria strains are a public health
concern. This emergence is caused by the overuse and misuse of antibiotics leading to the …

Practices and trends of machine learning application in nanotoxicology

I Furxhi, F Murphy, M Mullins, A Arvanitis, CA Poland - Nanomaterials, 2020 - mdpi.com
Machine Learning (ML) techniques have been applied in the field of nanotoxicology with
very encouraging results. Adverse effects of nanoforms are affected by multiple features …

Evaluating metal oxide nanoparticle (MeOx NP) toxicity with different types of nano descriptors mainly focusing on simple periodic table-based descriptors: a mini …

J Roy, K Roy - Environmental Science: Nano, 2023 - pubs.rsc.org
Given the rapid growth of nanotechnology, it is essential to know the hazardous effects of
metal oxide nanoparticles (MeOx NPs) posed to the living organisms within the ecosystem …

Precision nanotoxicology in drug development: Current trends and challenges in safety and toxicity implications of customized multifunctional nanocarriers for drug …

A Ahmad, M Imran, N Sharma - Pharmaceutics, 2022 - mdpi.com
The dire need for the assessment of human and environmental endangerments of
nanoparticulate material has motivated the formulation of novel scientific tools and …

Application of machine learning in nanotoxicology: a critical review and perspective

Y Zhou, Y Wang, W Peijnenburg… - Environmental …, 2024 - ACS Publications
The massive production and application of nanomaterials (NMs) have raised concerns
about the potential adverse effects of NMs on human health and the environment …