The effects of bioactive compounds from plant foods on mitochondrial function: A focus on apoptotic mechanisms

TY Forbes-Hernández, F Giampieri… - Food and Chemical …, 2014 - Elsevier
Mitochondria are essential organelles for cellular integrity and functionality maintenance
and their imparement is implicated in the development of a wide range of diseases …

Role of docosahexaenoic acid in the modulation of glial cells in Alzheimer's disease

D Heras-Sandoval, J Pedraza-Chaverri… - Journal of …, 2016 - Springer
Docosahexaenoic acid (DHA) is an omega-3 (ω-3) long-chain polyunsaturated fatty acid
(LCPUFA) relevant for brain function. It has largely been explored as a potential candidate to …

Mitochondria: omega-3 in the route of mitochondrial reactive oxygen species

KH Al-Gubory - The international journal of biochemistry & cell biology, 2012 - Elsevier
Mitochondria are the main organelles that produce reactive oxygen species (ROS).
Overproduction of ROS induces oxidative damage to macromolecules, including lipids, and …

Docosahexaenoic Acid as Master Regulator of Cellular Antioxidant Defenses: A Systematic Review

SM Borgonovi, S Iametti, M Di Nunzio - Antioxidants, 2023 - mdpi.com
Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid that benefits the prevention of
chronic diseases. Due to its high unsaturation, DHA is vulnerable to free radical oxidation …

Maternal linoleic acid-rich diet ameliorates bilirubin neurotoxicity in offspring mice

D Yan, XT Wu, X Chen, J Wang, F Ge, M Wu, J Wu… - Cell Death …, 2024 - nature.com
Hyperbilirubinaemia is a prevalent condition during the neonatal period, and if not promptly
and effectively managed, it can lead to severe bilirubin-induced neurotoxicity. Sunflower …

Caffeine prevents bilirubin-induced cytotoxicity in cultured newborn rat astrocytes

M Deliktaş, H Ergin, A Demiray, H Akça… - The Journal of …, 2019 - Taylor & Francis
Objective Unconjugated bilirubin (UCB) may cause neurotoxicity in preterm neonates due to
immaturity of UGT1A1 leading to bilirubin accumulation in the brain. Caffeine used in the …

BK channel opener protects cell viability by regulating reactive oxygen levels in astrocyte cells

C Coskun, O Tokgun - General physiology and biophysics, 2021 - gcris.pau.edu.tr
Astrocytes are greatly impacted by oxidative stress, which can also be related to
neurodegenerative diseases. Therefore, preventing the production of reactive oxygen …

Effect of docosahexaenoic acid and furan fatty acids on cytokinesis block micronucleus cytome assay biomarkers in astrocytoma cell lines under conditions of …

A Chua, P Thomas, C Wijesundera… - Environmental and …, 2014 - Wiley Online Library
Fatty acids from fish such as docosahexaenoic acid (DHA) are associated with improved
brain function, whereas furan fatty acids (FFAs) also found in fish oil at low levels (1%) are …

[PDF][PDF] Study of Some Biochemical Parameters in Epileptic Patients

DE Ibrahim, WKH Alhashemi - Al-Nahrain Journal of Science, 2019 - iasj.net
Epilepsy is a worldwide disease characterized by huge changes in several biochemical
parameters due to seizure the main symptoms of the disease. The aim of this study was to …

[HTML][HTML] Neuroprotective effect of ω-3 polyunsaturated fatty acids on bilirubin encephalopathy in vitro and in vivo

W Hao, J Song, G Li - … Medical Journal of Experimental and Clinical …, 2018 - ncbi.nlm.nih.gov
Background Bilirubin encephalopathy is a serious complication in neonatal jaundice and is
associated with high mortality and disability in newborns. The present study aimed to …