Red blood cell metabolism in vivo and in vitro

A D'Alessandro, AT Anastasiadi, VL Tzounakas… - Metabolites, 2023 - mdpi.com
Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

Oxidative stress in healthy and pathological red blood cells

F Orrico, S Laurance, AC Lopez, SD Lefevre… - Biomolecules, 2023 - mdpi.com
Red cell diseases encompass a group of inherited or acquired erythrocyte disorders that
affect the structure, function, or production of red blood cells (RBCs). These disorders can …

The red blood cell—inflammation vicious circle in sickle cell disease

E Nader, M Romana, P Connes - Frontiers in immunology, 2020 - frontiersin.org
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the β-globin
gene, leading to the production of an abnormal hemoglobin called hemoglobin S (HbS) …

Nitric oxide to fight viral infections

F Lisi, AN Zelikin, R Chandrawati - Advanced Science, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) that has quickly and …

Protective mechanisms of quercetin against myocardial ischemia reperfusion injury

YM Zhang, ZY Zhang, RX Wang - Frontiers in Physiology, 2020 - frontiersin.org
Quercetin has attracted more attention in recent years due to its protective role against
ischemia/reperfusion injury. Quercetin can alleviate oxidative stress injury through the …

The role of blood rheology in sickle cell disease

P Connes, T Alexy, J Detterich, M Romana… - Blood reviews, 2016 - Elsevier
Studies performed in the last decades have highlighted the need to better understand the
contribution of the endothelium, vascular function, oxidative stress, inflammation …

Decellularized blood vessel development: Current state-of-the-art and future directions

X Wang, V Chan, PR Corridon - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Vascular diseases contribute to intensive and irreversible damage, and current treatments
include medications, rehabilitation, and surgical interventions. Often, these diseases require …

Red blood cell dysfunction: a new player in cardiovascular disease

J Pernow, A Mahdi, J Yang, Z Zhou - Cardiovascular research, 2019 - academic.oup.com
The primary role of red blood cells (RBCs) is to transport oxygen to the tissues and carbon
dioxide to the lungs. However, emerging evidence suggests an important role of the RBC …

Physical properties of blood and their relationship to clinical conditions

T Alexy, J Detterich, P Connes, K Toth, E Nader… - Frontiers in …, 2022 - frontiersin.org
It has been long known that blood health heavily influences optimal physiological function.
Abnormalities affecting the physical properties of blood have been implicated in the …

[HTML][HTML] Sepsis-mediated renal dysfunction: pathophysiology, biomarkers and role of phytoconstituents in its management

A Balkrishna, S Sinha, A Kumar, V Arya… - Biomedicine & …, 2023 - Elsevier
Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …