Mesenchymal stem cells in fibrotic diseases—the two sides of the same coin

L Qin, N Liu, C Bao, D Yang, G Ma, W Yi… - Acta Pharmacologica …, 2023 - nature.com
Fibrosis is caused by extensive deposition of extracellular matrix (ECM) components, which
play a crucial role in injury repair. Fibrosis attributes to~ 45% of all deaths worldwide. The …

The issue of heterogeneity of MSC-based advanced therapy medicinal products–a review

AB Česnik, U Švajger - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Mesenchymal stromal stem cells (MSCs) possess a remarkable potential for numerous
clinical applications due to their unique properties including self-renewal …

[HTML][HTML] Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications

S Sharma, S Muthu, M Jeyaraman… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
With developments in the field of tissue engineering and regenerative medicine, the use of
biological products for the treatment of various disorders has come into the limelight among …

Adult mesenchymal stem cells from oral cavity and surrounding areas: types and biomedical applications

ME Cabaña-Muñoz, MJ Pelaz Fernández… - Pharmaceutics, 2023 - mdpi.com
Adult mesenchymal stem cells are those obtained from the conformation of dental structures
(DMSC), such as deciduous and permanent teeth and other surrounding tissues …

Mesenchymal stem cells in the treatment of osteogenesis imperfecta

E Lang, JA Semon - Cell Regeneration, 2023 - Springer
Osteogenesis imperfecta (OI) is a disease caused by mutations in different genes resulting
in mild, severe, or lethal forms. With no cure, researchers have investigated the use of cell …

Cell‐Based transplantation versus cell homing approaches for pulp‐dentin complex regeneration

GM Ahmed, EA Abouauf, N AbuBakr… - Stem cells …, 2021 - Wiley Online Library
Regenerative dentistry has paved the way for a new era for the replacement of damaged
dental tissues. Whether the causative factor is dental caries, trauma, or chemical insult, the …

Innovations in stem cell therapy for diabetic wound healing

J Ho, D Yue, U Cheema, HC Hsia… - Advances in Wound …, 2023 - liebertpub.com
Significance: The global burden of diabetic wounds, particularly diabetic foot ulcers,
continues to have large economic and social impact throughout the world. Current strategies …

[HTML][HTML] Mesenchymal Stromal Cells for Aging Cartilage Regeneration: A Review

KC Wu, YH Chang, DC Ding, SZ Lin - International Journal of Molecular …, 2024 - mdpi.com
Cartilage degeneration is a key feature of aging and osteoarthritis, characterized by the
progressive deterioration of joint function, pain, and limited mobility. Current treatments …

Modeling of the human bone environment: mechanical stimuli guide mesenchymal stem cell–extracellular matrix interactions

AR Pereira, A Lipphaus, M Ergin, S Salehi… - Materials, 2021 - mdpi.com
In bone tissue engineering, the design of in vitro models able to recreate both the chemical
composition, the structural architecture, and the overall mechanical environment of the …

[HTML][HTML] Mesenchymal stem cells-the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists

T Minev, S Balbuena, JM Gill, FM Marincola… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are recognized for their immunomodulatory capabilities,
tumor-homing abilities, and capacity to serve as carriers for therapeutic agents. This review …