Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

R Radi - Proceedings of the National Academy of Sciences, 2018 - National Acad Sciences
Oxygen-derived free radicals and related oxidants are ubiquitous and short-lived
intermediates formed in aerobic organisms throughout life. These reactive species …

Sources of vascular nitric oxide and reactive oxygen species and their regulation

J Tejero, S Shiva, MT Gladwin - Physiological reviews, 2019 - journals.physiology.org
Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Biochemistry of peroxynitrite and protein tyrosine nitration

G Ferrer-Sueta, N Campolo, M Trujillo… - Chemical …, 2018 - ACS Publications
Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …

[HTML][HTML] Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration

S Bartesaghi, R Radi - Redox biology, 2018 - Elsevier
In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine
nitration. Peroxynitrite is the product of the diffusion-controlled reaction between superoxide …

Recent progress of food‐derived bioactive peptides: Extraction, purification, function, and encapsulation

Y Jiang, J Sun, J Chandrapala, M Majzoobi… - Food …, 2024 - Wiley Online Library
Functional peptides constitute a class of small molecular peptide chains with specific
functions in biology and are typically composed of various amino acids. The chemical …

The effect of manganese nanoparticles on performance, redox reactions and epigenetic changes in turkey tissues

K Ognik, K Kozłowski, A Stępniowska, R Szlązak… - Animal, 2019 - cambridge.org
The hypothesis of the research was the assumption, that manganese nanoparticles can
affect the body in the same way as macromolecules. Their smaller size and greater …

[HTML][HTML] Antioxidant activities and protective effects of duck embryo peptides against H2 O2-induced oxidative damage in HepG2 cells

Y He, L Bu, H Xie, G Liang - Poultry Science, 2019 - Elsevier
Previous work showed that peptides from duck eggs incubated for 15 D presented high total
antioxidant activities. Here, this work explore the antioxidant activities of different segments …

Radiolysis studies of oxidation and nitration of tyrosine and some other biological targets by peroxynitrite-derived radicals

LK Folkes, S Bartesaghi, M Trujillo, P Wardman… - International Journal of …, 2022 - mdpi.com
The widespread interest in free radicals in biology extends far beyond the effects of ionizing
radiation, with recent attention largely focusing on reactions of free radicals derived from …

Role of nitric oxide in megakaryocyte function

A Asgari, P Jurasz - International Journal of Molecular Sciences, 2023 - mdpi.com
Megakaryocytes are the main members of the hematopoietic system responsible for
regulating vascular homeostasis through their progeny platelets, which are generally known …

A mitochondrial redox switch licenses the onset of morphogenesis in animals

U Kahlin, F Dalla Ricca, SJ Pillai, M Olivetta, KM Tharp… - bioRxiv, 2024 - biorxiv.org
Embryos undergo pre-gastrulation cleavage cycles to generate a critical cell mass before
transitioning to morphogenesis. The molecular underpinnings of this transition have …