Randomised clinical trials in critical care: past, present and future
Randomised clinical trials (RCTs) are the gold standard for providing unbiased evidence of
intervention effects. Here, we provide an overview of the history of RCTs and discuss the …
intervention effects. Here, we provide an overview of the history of RCTs and discuss the …
Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial
Purpose We compared dexamethasone 12 versus 6 mg daily for up to 10 days in patients
with coronavirus disease 2019 (COVID-19) and severe hypoxaemia in the international …
with coronavirus disease 2019 (COVID-19) and severe hypoxaemia in the international …
[HTML][HTML] An overview of methodological considerations regarding adaptive stopping, arm dropping, and randomization in clinical trials
A Granholm, BS Kaas-Hansen, T Lange… - Journal of clinical …, 2023 - Elsevier
Abstract Background and Objectives Adaptive features may increase flexibility and efficiency
of clinical trials, and improve participants' chances of being allocated to better interventions …
of clinical trials, and improve participants' chances of being allocated to better interventions …
[HTML][HTML] Effectiveness of a smartphone app to promote healthy weight gain, diet, and physical activity during pregnancy (HealthyMoms): randomized controlled trial
J Sandborg, E Söderström, P Henriksson… - JMIR mHealth and …, 2021 - mhealth.jmir.org
Background: Excessive gestational weight gain (GWG) during pregnancy is a major public
health concern associated with negative health outcomes for both mother and child …
health concern associated with negative health outcomes for both mother and child …
Effectiveness of a smartphone app (MINISTOP 2.0) integrated in primary child health care to promote healthy diet and physical activity behaviors and prevent obesity …
C Alexandrou, H Henriksson, M Henström… - International Journal of …, 2023 - Springer
Background Childhood overweight and obesity is a public health priority. We have
previously reported the efficacy of a parent-oriented mobile health (mHealth) app-based …
previously reported the efficacy of a parent-oriented mobile health (mHealth) app-based …
[HTML][HTML] Just a matter of taste? Understanding rationalizations for dairy consumption and their associations with sensory expectations of plant-based milk alternatives
Although knowledge surrounding the obstacles omnivorous consumers face when
substituting meat products with plant-based alternatives has increased dramatically, less is …
substituting meat products with plant-based alternatives has increased dramatically, less is …
Compliance with recommendations limiting COVID-19 contagion among university students in Sweden: associations with self-reported symptoms, mental health and …
Aims: The COVID-19 containment strategy in Sweden uses public health recommendations
relying on personal responsibility for compliance. Universities were one of few public …
relying on personal responsibility for compliance. Universities were one of few public …
The p-Value Debate and Statistical (Mal) practice-Implications for the Agricultural and Food Economics Community
A vivid debate is ongoing in the scientific community about statistical malpractice and the
related publication bias. No general consensus exists on the consequences and this is …
related publication bias. No general consensus exists on the consequences and this is …
Effectiveness of a digital intervention versus alcohol information for online help-seekers in Sweden: a randomised controlled trial
M Bendtsen, K Åsberg, J McCambridge - BMC medicine, 2022 - Springer
Abstract Background The ubiquity of Internet connectivity, and widespread unmet needs,
requires investigations of digital interventions for people seeking help with their drinking …
requires investigations of digital interventions for people seeking help with their drinking …
Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID–ICU trial
NC Andersen-Ranberg, LM Poulsen, A Perner… - Intensive Care …, 2023 - Springer
Abstract Purpose The AID–ICU trial was a randomised, blinded, placebo-controlled trial
investigating effects of haloperidol versus placebo in acutely admitted, adult patients …
investigating effects of haloperidol versus placebo in acutely admitted, adult patients …