Pembrolizumab interferes with the differentiation of human FOXP3+–induced T regulatory cells, but not with FOXP3 stability, through activation of mTOR
V Sasidharan Nair, SM Toor, G Taouk… - The Journal of …, 2020 - journals.aai.org
Abstract Programmed cell death 1 (PD-1) is critical for T regulatory cells (Tregs) to maintain
peripheral tolerance to self-antigens. In the tumor microenvironment, interaction between PD …
peripheral tolerance to self-antigens. In the tumor microenvironment, interaction between PD …