Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Millions of cases of tuberculosis (TB) go undiagnosed each year. Better diagnostic tools are
urgently needed. Biomarker-based or multiple marker biosignature-based tests, ideally …

Despite substantial differences in ethnicities, habits, cultures, the prevalence of traditional
cardiovascular risk factors and affordable therapies, atherosclerosis remains the major …

Recent research suggests that risk for chronic diseases of aging including cardiovascular
disease, diabetes, and even cancer can be programmed early in the lifespan as a result of …

Chronic inflammation has been proposed as having a prominent role in the construction of
social inequalities in health. Disentangling the effects of early life and adulthood social …

Severe socioeconomic deprivation (SED) and adverse childhood experiences (ACE) are
significantly associated with the development in adulthood of (i) enhanced inflammatory …

Background The link between housing and health is well established and long-standing,
however much of the evidence relies on self-reported health measures. While these are …

Background Inflammation plays a central role in cardiometabolic disease and may represent
a mechanism linking low socioeconomic status (SES) in early life and adverse …

Background Studies have explored the relationship between social class and health for
decades. However, the underlying mechanism between the two remains not fully …

Objectives It has been estimated that over 50% of the premature deaths occurring in
Western countries can be attributed to causes rooted in lifestyle. In turn, leading a healthy …