Point-of-care testing of infectious diseases: recent advances

M Shang, J Guo, J Guo - Sensors & Diagnostics, 2023 - pubs.rsc.org
Infectious diseases have seriously threatened human health and caused enormous losses
to the global economy. Rapid and accurate diagnosis of pathogens is crucial to the timely …

Long-acting injectable drugs for HIV-1 pre-exposure prophylaxis: considerations for Africa

E Moyo, G Murewanhema, G Musuka… - Tropical Medicine and …, 2022 - mdpi.com
Sub-Saharan Africa carries the highest burden of HIV-1 and AIDS. About 39% of all new
infections in the world in 2020 were in this region. Oral PrEP was found to be very effective …

Sensitive and quantitative point-of-care HIV viral load quantification from blood using a power-free plasma separation and portable magnetofluidic polymerase chain …

HT Ngo, M Jin, AY Trick, FE Chen, L Chen… - Analytical …, 2022 - ACS Publications
Point-of-care (POC) HIV viral load (VL) tests are needed to enhance access to HIV VL
testing in low-and middle-income countries (LMICs) and to enable HIV VL self-testing at …

Effect of two counseling interventions on self-reported alcohol consumption, alcohol biomarker phosphatidylethanol (PEth), and viral suppression among persons …

JA Hahn, R Fatch, NI Emenyonu, N Sanyu… - Drug and alcohol …, 2023 - Elsevier
Purpose To test the efficacy of two interventions to reduce alcohol use and increase viral
suppression compared to a control in persons with HIV (PWH). Methods In a three-arm (1: 1 …

[HTML][HTML] Development of anti-HIV therapeutics: from conventional drug discovery to cutting-edge technology

Y Sun, L Wang - Pharmaceuticals, 2024 - mdpi.com
The efforts to discover HIV therapeutics have continued since the first human
immunodeficiency virus (HIV) infected patient was confirmed in the 1980s. Ten years later …

The viral load monitoring cascade in HIV treatment programmes in sub-Saharan Africa: a systematic review

A Kippen, L Nzimande, D Gareta, C Iwuji - BMC Public Health, 2024 - Springer
Abstract Background The United Nations' 95-95-95 (95% of people with HIV being aware of
their diagnosis, 95% of those aware of their diagnosis being on treatment and 95 …

Machine learning to predict virological failure among HIV patients on antiretroviral therapy in the University of Gondar Comprehensive and Specialized Hospital, in …

DN Mamo, TM Yilma, M Fekadie, Y Sebastian… - BMC Medical Informatics …, 2023 - Springer
Background Treatment with effective antiretroviral therapy (ART) reduces viral load as well
as HIV-related morbidity and mortality in HIV-positive patients. Despite the expanded …

“After viral load testing, I get my results so I get to know which path my life is taking me”: qualitative insights on routine centralized and point-of-care viral load testing in …

SRW Qian, SA Hassan, AJ Scallon, P Oyaro… - BMC Health Services …, 2022 - Springer
Background Viral suppression (VS) is a marker of effective HIV therapy, and viral load (VL)
testing is critical for treatment monitoring, especially in high-risk groups such as children and …

Economic evaluation of integrated services for non-communicable diseases and HIV: costs and client outcomes in rural Malawi

EB Wroe, B Mailosi, N Price, C Kachimanga, A Shah… - BMJ open, 2022 - bmjopen.bmj.com
Objective To evaluate the costs and client outcomes associated with integrating screening
and treatment for non-communicable diseases (NCDs) into HIV services in a rural and …

The frequency and predictors of unsuppressed HIV viral load among people with HIV in Nyaruguru District, Rwanda

F Hakizayezu, E Biracyaza, H Niyompano… - HIV/AIDS-Research …, 2022 - Taylor & Francis
Background By the end of 2015, epidemiological studies approximated 37 million people
living with HIV (PLHIV) and 46.3% of them were initiated to antiretroviral therapies. From the …