Human rhinoviruses (HRVs), first discovered in the 1950s, are responsible for more than
one-half of cold-like illnesses and cost billions of dollars annually in medical visits and …

The airway epithelium acts as a frontline defense against respiratory viruses, not only as a
physical barrier and through the mucociliary apparatus but also through its immunological …

Asthma and chronic obstructive pulmonary disease (COPD) are major causes of global
morbidity and mortality worldwide. The clinical course of both asthma and COPD are …

Rhinoviruses are the major cause of the common cold and a trigger of acute asthma
exacerbations. Whether these exacerbations result from direct infection of the lower airway …

Asthma remains an important human disease that is responsible for substantial worldwide
morbidity and mortality. The causes of asthma are multifactorial and include a complex mix …

Virus infections, the majority of which are rhinovirus infections, are the major cause of
asthma exacerbations. Treatment is unsatisfactory, and the pathogenesis unclear. Lower …

Human rhinoviruses (HRVs) are well‐recognised causes of common colds and associated
upper respiratory tract complications such as sinusitis and otitis media. This article reviews …

Common colds are associated with exacerbations of chronic obstructive pulmonary disease
(COPD). However, the role of the common cold virus (human rhinovirus) in the production of …

Rhinoviruses (RV) are the major cause of the common cold and acute exacerbations of
asthma and chronic obstructive pulmonary disease. Toll-like receptors (TLRs) are a …

Background: Respiratory viruses, predominantly rhinoviruses are the major cause of asthma
exacerbations. Impaired production of interferon‐β in rhinovirus infected bronchial epithelial …