Cytosolic Ca2+ buffers

B Schwaller - Cold Spring Harbor perspectives in biology, 2010 - cshperspectives.cshlp.org
“Ca2+ buffers,” a class of cytosolic Ca2+-binding proteins, act as modulators of short-lived
intracellular Ca2+ signals; they affect both the temporal and spatial aspects of these …

Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis

I Ingold, C Berndt, S Schmitt, S Doll, G Poschmann… - Cell, 2018 - cell.com
Selenoproteins are rare proteins among all kingdoms of life containing the 21 st amino acid,
selenocysteine. Selenocysteine resembles cysteine, differing only by the substitution of …

Cytosolic Ca2+ buffers are inherently Ca2+ signal modulators

B Schwaller - Cold Spring Harbor perspectives in biology, 2020 - cshperspectives.cshlp.org
For precisely regulating intracellular Ca2+ signals in a time-and space-dependent manner,
cells make use of various components of the “Ca2+ signaling toolkit,” including Ca2+ entry …

Parvalbumin deficiency affects network properties resulting in increased susceptibility to epileptic seizures

B Schwaller, IV Tetko, P Tandon, DC Silveira… - Molecular and Cellular …, 2004 - Elsevier
Networks of GABAergic interneurons are of utmost importance in generating and promoting
synchronous activity and are involved in producing coherent oscillations. These neurons are …

Secondary epileptogenesis: Common to see, but possible to treat?

Y Shen, Y Gong, Y Ruan, Z Chen, C Xu - Frontiers in neurology, 2021 - frontiersin.org
Secondary epileptogenesis is a common phenomenon in epilepsy, characterized by
epileptiform discharges from the regions outside the primary focus. It is one of the major …

Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus

HE Scharfman, AL Sollas, JH Goodman - Neuroscience, 2002 - Elsevier
Although it is now established that neurogenesis of dentate gyrus granule cells increases
after experimental seizures, little is currently known about the function of the new granule …

Regional expressions of Fos-like immunoreactivity in rat cerebral cortex after stress; restraint and intraperitoneal lipopolysaccharide

C Yokoyama, K Sasaki - Brain research, 1999 - Elsevier
To demonstrate regional activation in the rat cerebral cortex related to stress-evoked
neuroendocrine response, Fos expression in both the cerebral cortex and hypothalamic …

Expansion of epileptogenic networks via neuroplasticity in neural mass models

E Köksal-Ersöz, P Benquet… - PLOS Computational …, 2024 - journals.plos.org
Neuroplasticity refers to functional and structural changes in brain regions in response to
healthy and pathological activity. Activity dependent plasticity induced by epileptic activity …

Generalization of seizures parallels the formation of “dark” neurons in the hippocampus and pontine reticular formation after focal–cortical application of 4 …

P Baracskay, Z Szepesi, G Orbán, G Juhász, A Czurkó - Brain research, 2008 - Elsevier
Distribution and time course of the occurrence of “dark” neurons were compared with the
EEG activity and behavior of rats during 4-aminopyridine (4-AP) induced epileptic seizures …

Modification of ionotropic glutamate receptor–mediated processes in the rat hippocampus following repeated, brief seizures

S Borbély, E Dobó, D Czégé, E Molnár, M Bakos… - Neuroscience, 2009 - Elsevier
The seizure-induced molecular and functional alterations of glutamatergic transmission in
the hippocampus have been investigated. Daily repeated epileptic seizures were induced …