Role of microRNAs in Immune Regulation with Translational and Clinical Applications

Z Gaál - International Journal of Molecular Sciences, 2024 - mdpi.com
MicroRNAs (miRNAs) are 19–23 nucleotide long, evolutionarily conserved noncoding RNA
molecules that regulate gene expression at the post-transcriptional level. In this review …

Association of AIRE (rs2075876), but not CTLA4 (rs231775) polymorphisms with systemic lupus erythematosus

SA Alghamdi, SW Kattan, EA Toraih, MG Alrowaili… - Gene, 2021 - Elsevier
Background The AIRE (rs2075876) and CTLA4 (rs231775) variants have a crucial function
in controlling the negative selection and suppression of T lymphocytes. Numerous reports …

Association of GSTP1 p. Ile105Val (rs1695, c. 313A> G) variant with the risk of breast carcinoma among Egyptian women

MM Youssef, AM Elsaid, RA El-Saeed, RT Mukhlif… - Biochemical …, 2021 - Springer
Several reports examined the association of the GSTP1 p. Ile105Val (rs1695, c. 313A> G)
variant with the elevated risk of multiple cancerous diseases involving breast carcinoma, but …

MIR17HG polymorphisms contribute to high-altitude pulmonary edema susceptibility in the Chinese population

L Si, H Wang, Y Jiang, Y Yi, R Wang, Q Long… - Scientific Reports, 2022 - nature.com
High-altitude pulmonary edema (HAPE) is a common acute altitude sickness. This study was
designed to investigate the effect of MIR17HG polymorphisms on HAPE risk in the Chinese …

MicroRNA-17-92a-1 host gene (MIR17HG) expression signature and rs4284505 variant association with alopecia areata: a case–control study

S Faisal, EA Toraih, LM Atef, R Hassan, MM Fouad… - Genes, 2022 - mdpi.com
Accumulating evidence indicates the implication of microRNAs (miRs) in cutaneous and hair
follicle immunobiology. We evaluated, for the first time, the miR-17-92a-1 cluster host gene …

Association of microRNA-34a rs2666433 (A/G) Variant with Systemic Lupus Erythematosus in Female Patients: A Case-Control Study

NM Ismail, EA Toraih, MHS Mohammad… - Journal of Clinical …, 2021 - mdpi.com
Several microRNAs (miRNAs) are associated with autoimmune disease susceptibility and
phenotype, including systemic lupus erythematosus (SLE). We aimed to explore for the first …

Analysis of MIR27A (rs11671784) Variant Association with Systemic Lupus Erythematous

ZA Khired, SW Kattan, AK Alzahrani, AJ Milebary… - Life, 2023 - mdpi.com
Multiple microRNAs (miRs) are associated with systemic autoimmune disease susceptibility/
phenotype, including systemic lupus erythematosus (SLE). With this work, we aimed to …

NF1-Related MicroRNA Gene Polymorphisms and the Susceptibility to Soft Tissue Sarcomas: A Case–Control Study

P Zhang, L Huang, X Li, F Hu, X Niu, Y Sun… - DNA and Cell …, 2023 - liebertpub.com
Soft tissue sarcomas (STS) are rare malignant tumors of mesenchymal origin, which are
easy to metastasize and relapse and are a great threat to human health. In our previous …