Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high intratumoral
heterogeneity. Recent studies revealed that TNBC patients might comprise cells with distinct …

Background: The global alliance for genomics and healthcare facilities provides innovative
solutions to expedite research and clinical practices for complex and incurable health …

Triple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer.
Various endeavor has been made to explore the molecular biology basis of TNBC. Herein …

Breast cancer (BC) represents a molecularly and clinically heterogeneous disease. Recent
progress in immunotherapy has provided a glimmer of hope for several BC subtypes. The …

Epithelial-mesenchymal plasticity plays a critical role in many solid tumor types as a
mediator of metastatic dissemination and treatment resistance. In addition, there is also a …

Breast cancer is characterized as being a heterogeneous pathology with a broad phenotype
variability. Breast cancer subtypes have been developed in order to capture some of this …

Introduction Tumorigenesis in breast cancers usually accompanied by the dysregulation of
transcription factors (TFs). Abnormal amplification of TFs leads aberrant expression of its …

Background: Tamoxifen-adapted MCF-7-Tam cells represent an in-vitro model for acquired
tamoxifen resistance, which is still a problem in clinics. We here investigated the correlation …

Breast cancer is a heterogeneous disease that arises as a multi-stage process involving
multiple cell types. Patients diagnosed with the same clinical stage and pathological …

Background In recent years, researchers have made significant strides in understanding the
heterogeneity of breast cancer and its various subtypes. However, the wealth of genomic …