Recent advances in the synthesis of pyrrolo [1, 2-a] indoles and their derivatives

YG Shelke, PE Hande, SJ Gharpure - Organic & Biomolecular …, 2021 - pubs.rsc.org
The pyrrolo [1, 2-a] indole unit is a privileged heterocycle found in numerous natural
products and has been shown to exhibit diverse pharmacological properties. Thus, recent …

Pyrroloindoles as Therapeutically Invaluable Agents: A Review on their Diverse Synthetic Methodologies

SS Ramesh, R Gattu, S Ramesh - Asian Journal of Organic …, 2024 - Wiley Online Library
In the realm of medicinal chemistry, heterocyclic compounds play a vital role due to their
diverse pharmacological properties, especially, pyrroloindoles standing out as crucial motifs …

Ruthenium-catalysed one-pot regio-and diastereoselective synthesis of pyrrolo [1, 2-a] indoles via cascade C–H functionalization/annulation

S Singh, HH Butani, DD Vachhani, A Shah… - Chemical …, 2017 - pubs.rsc.org
A cascade approach has been developed towards dual C–C bond formation via consecutive
C–H functionalization/cyclization giving access to pyrrolo [1, 2-a] indoles in a highly regio …

Organocatalytic Asymmetric Tandem α‐Aminooxylation–Henry Reactions for the Synthesis of 1,2‐Diols: Total Synthesis of (–)‐lthreo‐Sphinganine

Y Garg, R Kaur, S Kumar Pandey - European Journal of …, 2017 - Wiley Online Library
A new and rapid asymmetric synthesis of anti‐and syn‐β, γ‐dihydroxynitroalkanes through
an organocatalytic tandem α‐aminooxylation–Henry reaction is described. The target diol …

Enantioselective total synthesis of cis-(+)-and trans-(+)-disparlure

Y Garg, AK Tiwari, SK Pandey - Tetrahedron Letters, 2017 - Elsevier
An expedient enantioselective synthetic approach for the gypsy moth sex-attractant
pheromone cis-(+)-1 and trans-(+)-disparlure 2 is described employing the optimized …

An enantioselective approach to 3-substituted pyrrolidines: Asymmetric synthesis for pyrrolidine core of serotonin norepinephrine reuptake inhibitors (SNRIs)

Y Garg, P Sharma, SK Pandey - Tetrahedron Letters, 2017 - Elsevier
A novel and efficient synthetic approach to enantiopure 3-substituted pyrrolidine skeleton
from readily available (S)-PMB glycidyl ether as a starting material and its application to the …

Antiplasmodial bis-indole alkaloids from the bark of flindersia pimenteliana

LP Robertson, L Lucantoni, VM Avery… - Planta Medica, 2020 - thieme-connect.com
Three new (1–3) and 2 known (4–5) bis-indole alkaloids were identified from the bark of
Flindersia pimenteliana (Rutaceae). The structures of 1–3 were elucidated on the basis of …

Asymmetric total synthesis of phomonol

S Gahalawat, SK Pandey - Tetrahedron Letters, 2017 - Elsevier
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Efficient synthesis of (−)-(R)-and (+)-(S)-rolipram

R Kaur, SK Pandey - Tetrahedron letters, 2017 - Elsevier
A novel, efficient and protecting group free enantioselective synthetic approach of (−)-(R)-1
and (+)-(S)-rolipram 2 is described employing the organocatalyzed asymmetric Michael …

Brønsted Acid Catalyzed Intramolecular Friedel-Crafts Addition of Tertiary Allylic Alcohols to Indoles.

BH Wakefield, R Barnes, T Brown… - Journal of the South …, 2022 - search.ebscohost.com
Abstract An intermolecular Friedel-Crafts alkylation of indole and tertiary allylic alcohols has
been developed. The allylic alcohols were synthesized using a two-step procedure, then …