Plant-derived natural products for drug discovery: current approaches and prospects

N Nasim, IS Sandeep, S Mohanty - The Nucleus, 2022 - Springer
Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …

Recent progress in polysaccharides from Panax ginseng CA Meyer

M Guo, S Shao, D Wang, D Zhao, M Wang - Food & function, 2021 - pubs.rsc.org
Panax ginseng CA Meyer (P. ginseng) has a long history of medicinal use and can treat a
variety of diseases. P. ginseng contains a variety of active ingredients, such as saponins …

From traditional ethnopharmacology to modern natural drug discovery: A methodology discussion and specific examples

S Pirintsos, A Panagiotopoulos, M Bariotakis… - Molecules, 2022 - mdpi.com
Ethnopharmacology, through the description of the beneficial effects of plants, has provided
an early framework for the therapeutic use of natural compounds. Natural products, either in …

Multi-step in silico discovery of natural drugs against COVID-19 targeting main protease

EB Elkaeed, FS Youssef, IH Eissa, H Elkady… - International Journal of …, 2022 - mdpi.com
In continuation of our antecedent work against COVID-19, three natural compounds, namely,
Luteoside C (130), Kahalalide E (184), and Streptovaricin B (278) were determined as the …

A multistage in silico study of natural potential inhibitors targeting SARS-CoV-2 main protease

EB Elkaeed, IH Eissa, H Elkady, A Abdelalim… - International Journal of …, 2022 - mdpi.com
Among a group of 310 natural antiviral natural metabolites, our team identified three
compounds as the most potent natural inhibitors against the SARS-CoV-2 main protease …

Ginsenoside compound K: Insights into recent studies on pharmacokinetics and health-promoting activities

A Sharma, HJ Lee - Biomolecules, 2020 - mdpi.com
Ginseng (Panax ginseng) is an herb popular for its medicinal and health properties.
Compound K (CK) is a secondary ginsenoside biotransformed from major ginsenosides …

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10

IH Eissa, MM Khalifa, EB Elkaeed, EE Hafez… - Molecules, 2021 - mdpi.com
In continuation of our previous effort, different in silico selection methods were applied to
310 naturally isolated metabolites that exhibited antiviral potentialities before. The applied …

Oxidative stress and ginsenosides: An update on the molecular mechanisms

B He, D Chen, X Zhang, R Yang, Y Yang… - Oxidative medicine …, 2022 - Wiley Online Library
Ginsenosides are a class of active components extracted from ginseng plants (such as
Panax ginseng, Panax quinquefolium, and Panax notoginseng). Ginsenosides have …

[HTML][HTML] Traditional ancient Egyptian medicine: A review

AM Metwaly, MM Ghoneim, IH Eissa… - Saudi journal of …, 2021 - Elsevier
The ancient Egyptians practiced medicine with highly professional methods. They had
advanced knowledge of anatomy and surgery. Also, they treated a lot of diseases including …

In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro)

MS Alesawy, AE Abdallah, MS Taghour, EB Elkaeed… - Molecules, 2021 - mdpi.com
The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the “COVID-
19” disease that has been declared by WHO as a global emergency. The pandemic, which …