Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissues
Memory T and B cells in tissues are essential for protective immunity. Here, we performed a
comprehensive analysis of the tissue distribution, phenotype, durability, and transcriptional …
comprehensive analysis of the tissue distribution, phenotype, durability, and transcriptional …
Accurate quantification of single-cell and single-nucleus RNA-seq transcripts using distinguishing flanking k-mers
In single-cell and single-nucleus RNA sequencing, the coexistence of nascent
(unprocessed) and mature (processed) mRNA poses challenges in accurate read mapping …
(unprocessed) and mature (processed) mRNA poses challenges in accurate read mapping …
Biophysically interpretable inference of cell types from multimodal sequencing data
Multimodal, single-cell genomics technologies enable simultaneous measurement of
multiple facets of DNA and RNA processing in the cell. This creates opportunities for …
multiple facets of DNA and RNA processing in the cell. This creates opportunities for …
Characterization of prostate macrophage heterogeneity, foam cell markers, and CXCL17 upregulation in a mouse model of steroid hormone imbalance
SV Silver, KJ Tucker, RE Vickman, NA Lanman… - Scientific Reports, 2024 - nature.com
Benign prostatic hyperplasia (BPH) is a prevalent age-related condition often characterized
by debilitating urinary symptoms. Its etiology is believed to stem from hormonal imbalance …
by debilitating urinary symptoms. Its etiology is believed to stem from hormonal imbalance …
Accurate quantification of nascent and mature RNAs from single-cell and single-nucleus RNA-seq
In single-cell and single-nucleus RNA sequencing (RNA-seq), the coexistence of nascent
(unprocessed) and mature (processed) messenger RNA (mRNA) poses challenges in …
(unprocessed) and mature (processed) messenger RNA (mRNA) poses challenges in …
[PDF][PDF] Accurate quantification of single-cell and single-nucleus RNA-seq transcripts using distinguishing flanking k-mers
In single-cell and single-nucleus RNA sequencing, the coexistence of nascent
(unprocessed) and mature (processed) mRNA poses challenges in accurate read mapping …
(unprocessed) and mature (processed) mRNA poses challenges in accurate read mapping …
[HTML][HTML] The impact of package selection and versioning on single-cell RNA-seq analysis
Standard single-cell RNA-sequencing analysis (scRNA-seq) workflows consist of converting
raw read data into cell-gene count matrices through sequence alignment, followed by …
raw read data into cell-gene count matrices through sequence alignment, followed by …
Efficient and accurate detection of viral sequences at single-cell resolution reveals putative novel viruses perturbing host gene expression
There are an estimated 300,000 mammalian viruses from which infectious diseases in
humans may arise. They inhabit human tissues such as the lungs, blood, and brain and …
humans may arise. They inhabit human tissues such as the lungs, blood, and brain and …
Stochastic Modeling of Biophysical Responses to Perturbation
Recent advances in high-throughput, multi-condition experiments allow for genome-wide
investigation of how perturbations affect transcription and translation in the cell across …
investigation of how perturbations affect transcription and translation in the cell across …
A human commons cell atlas reveals cell type specificity for OAS1 isoforms
We describe an open source Human Commons Cell Atlas comprising 2.9 million cells
across 27 tissues that can be easily updated and that is structured to facilitate custom …
across 27 tissues that can be easily updated and that is structured to facilitate custom …