Norepinephrine links astrocytic activity to regulation of cortical state

ME Reitman, V Tse, X Mi, DD Willoughby… - Nature …, 2023 - nature.com
Cortical state, defined by population-level neuronal activity patterns, determines sensory
perception. While arousal-associated neuromodulators—including norepinephrine (NE) …

A hierarchy of linguistic predictions during natural language comprehension

M Heilbron, K Armeni, JM Schoffelen… - Proceedings of the …, 2022 - National Acad Sciences
Understanding spoken language requires transforming ambiguous acoustic streams into a
hierarchy of representations, from phonemes to meaning. It has been suggested that the …

Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses

SM O'Toole, HK Oyibo, GB Keller - Neuron, 2023 - cell.com
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …

Associative and predictive hippocampal codes support memory-guided behaviors

C Liu, R Todorova, W Tang, A Oliva, A Fernandez-Ruiz - Science, 2023 - science.org
Episodic memory involves learning and recalling associations between items and their
spatiotemporal context. Those memories can be further used to generate internal models of …

[HTML][HTML] Cooperative thalamocortical circuit mechanism for sensory prediction errors

S Furutachi, AD Franklin, AM Aldea, TD Mrsic-Flogel… - Nature, 2024 - nature.com
The brain functions as a prediction machine, utilizing an internal model of the world to
anticipate sensations and the outcomes of our actions. Discrepancies between expected …

The locus coeruleus broadcasts prediction errors across the cortex to promote sensorimotor plasticity

R Jordan, GB Keller - Elife, 2023 - elifesciences.org
Prediction errors are differences between expected and actual sensory input and are
thought to be key computational signals that drive learning related plasticity. One way that …

A visual pathway for skylight polarization processing in Drosophila

BJ Hardcastle, JJ Omoto, P Kandimalla, BCM Nguyen… - Elife, 2021 - elifesciences.org
Many insects use patterns of polarized light in the sky to orient and navigate. Here, we
functionally characterize neural circuitry in the fruit fly, Drosophila melanogaster, that …

Centripetal integration of past events in hippocampal astrocytes regulated by locus coeruleus

P Rupprecht, SN Duss, D Becker, CM Lewis… - Nature …, 2024 - nature.com
An essential feature of neurons is their ability to centrally integrate information from their
dendrites. The activity of astrocytes, in contrast, has been described as mostly …

[HTML][HTML] Brain-wide neural activity underlying memory-guided movement

S Chen, Y Liu, ZA Wang, J Colonell, LD Liu, H Hou… - Cell, 2024 - cell.com
Behavior relies on activity in structured neural circuits that are distributed across the brain,
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …

Cortical processing of flexible and context-dependent sensorimotor sequences

D Xu, M Dong, Y Chen, AM Delgado, NC Hughes… - Nature, 2022 - nature.com
The brain generates complex sequences of movements that can be flexibly configured
based on behavioural context or real-time sensory feedback, but how this occurs is not fully …