Myeloproliferative neoplasms

JL Spivak - New England Journal of Medicine, 2017 - Mass Medical Soc
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Clinical insights into the origins of thrombosis in myeloproliferative neoplasms

AR Moliterno, YZ Ginzburg… - Blood, The Journal of the …, 2021 - ashpublications.org
Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), polycythemia
vera, essential thrombocythemia, and primary myelofibrosis, are hematopoietic stem cell …

Impact of calreticulin mutations on clinical and hematological phenotype and outcome in essential thrombocythemia

G Rotunno, C Mannarelli, P Guglielmelli… - Blood, The Journal …, 2014 - ashpublications.org
Mutations in the calreticulin (CALR) gene were recently discovered in patients with essential
thrombocythemia (ET) lacking the JAK2 V617F and MPL W515 mutations, but no information …

Bleeding, thrombosis, and anticoagulation in myeloproliferative neoplasms (MPN): analysis from the German SAL-MPN-registry

A Kaifie, M Kirschner, D Wolf, C Maintz, M Hänel… - Journal of hematology & …, 2016 - Springer
Abstract Background Patients with Ph-negative myeloproliferative neoplasms (MPN), such
as polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis …

How I treat polycythemia vera

JL Spivak - Blood, The Journal of the American Society of …, 2019 - ashpublications.org
Since its discovery, polycythemia vera (PV) has challenged clinicians responsible for its
diagnosis and management and scientists investigating its pathogenesis. As a clonal …

Splanchnic vein thrombosis associated with myeloproliferative neoplasms

D Tremblay, A Winters, JD Beckman, L Naymagon… - Thrombosis …, 2022 - Elsevier
Splanchnic vein thrombosis (SVT) in the setting of myeloproliferative neoplasm (MPN) is a
unique clinical entity that requires close interdisciplinary coordination for proper diagnosis …

Molecular profiling and risk classification of patients with myeloproliferative neoplasms and splanchnic vein thromboses

PE Debureaux, B Cassinat, J Soret-Dulphy… - Blood …, 2020 - ashpublications.org
Myeloproliferative neoplasms (MPNs) are the most frequent underlying causes of splanchnic
vein thromboses (SVTs). MPN patients with SVTs (MPN-SVT) often have a unique …

Sex determines the presentation and outcomes in MPN and is related to sex-specific differences in the mutational burden

T Karantanos, S Chaturvedi, EM Braunstein… - Blood …, 2020 - ashpublications.org
The factors underlying the variable presentation and clinical course of myeloproliferative
neoplasms (MPNs) remain unclear. The aim of this study was to evaluate the independent …

[HTML][HTML] Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: an analysis by the MPN QOL International …

HL Geyer, H Kosiorek, AC Dueck, R Scherber… - …, 2017 - ncbi.nlm.nih.gov
The myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia
and myelofibrosis, are distinguished by their debilitating symptom profiles, life-threatening …

Age-related differences in disease characteristics and clinical outcomes in polycythemia vera

BL Stein, S Saraf, U Sobol, A Halpern… - Leukemia & …, 2013 - Taylor & Francis
The natural history and prognosis for young patients with polycythemia vera (PV) in the post-
JAK2 V617F era are not well defined. Therefore, we retrospectively analyzed disease …