N Cullin, CA Antunes, R Straussman… - Cancer Cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically interacts with the host across multiple body sites. Host-microbiome interactions impact …
AB Dohlman, J Klug, M Mesko, IH Gao, SM Lipkin… - Cell, 2022 - cell.com
Fungal microorganisms (mycobiota) comprise a small but immunoreactive component of the human microbiome, yet little is known about their role in human cancers. Pan-cancer …
J Yang, H Wei, Y Zhou, CH Szeto, C Li, Y Lin… - Gastroenterology, 2022 - Elsevier
Background and Aims Dietary fat intake is associated with increased risk of colorectal cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …
D Denk, FR Greten - Trends in Cancer, 2022 - cell.com
An inflammatory microenvironment, either conferred by an underlying chronic overt or smoldering inflammatory condition constitutes a prerequisite and fuel to essentially all …
Y Cheng, Z Ling, L Li - Frontiers in immunology, 2020 - frontiersin.org
The intestinal microbiota, composed of a large population of microorganisms, is often considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …
N Wang, JY Fang - Trends in Microbiology, 2023 - cell.com
Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …
NN Liu, N Jiao, JC Tan, Z Wang, D Wu, AJ Wang… - Nature …, 2022 - nature.com
Despite recent progress in our understanding of the association between the gut microbiome and colorectal cancer (CRC), multi-kingdom gut microbiome dysbiosis in CRC …
A Janney, F Powrie, EH Mann - Nature, 2020 - nature.com
Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is characterized by the accumulation of mutations and a dysregulated immune response. Up to …
NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the second leading cause of cancer death. Arising through three major pathways, including …