Chemogenetics for cell-type-specific modulation of signalling and neuronal activity
Chemogenetics is an approach for engineering proteins to enable their modulation by
otherwise inert small molecules. Although kinases, enzymes and ion channels have been …
otherwise inert small molecules. Although kinases, enzymes and ion channels have been …
Connecting circuits with networks in addiction neuroscience: A salience network perspective
Human neuroimaging has demonstrated the existence of large-scale functional networks in
the cerebral cortex consisting of topographically distant brain regions with functionally …
the cerebral cortex consisting of topographically distant brain regions with functionally …
The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation
Measures of fMRI resting-state functional connectivity (rs-FC) are an essential tool for basic
and clinical investigations of fronto-limbic circuits. Understanding the relationship between …
and clinical investigations of fronto-limbic circuits. Understanding the relationship between …
Multimodal imaging for validation and optimization of ion channel-based chemogenetics in nonhuman primates
Y Hori, Y Nagai, Y Hori, K Oyama… - Journal of …, 2023 - Soc Neuroscience
Chemogenetic tools provide an opportunity to manipulate neuronal activity and behavior
selectively and repeatedly in nonhuman primates (NHPs) with minimal invasiveness …
selectively and repeatedly in nonhuman primates (NHPs) with minimal invasiveness …
[HTML][HTML] Strength of activation and temporal dynamics of bioluminescent-optogenetics in response to systemic injections of the luciferin
EF Murphy, A Means, C Li, H Baez, M Gomez-Ramirez - NeuroImage, 2024 - Elsevier
Abstract BioLuminescent OptoGenetics (“BL-OG”) is a chemogenetic method that can evoke
optogenetic reactions in the brain non-invasively. In BL-OG, an enzyme that catalyzes a light …
optogenetic reactions in the brain non-invasively. In BL-OG, an enzyme that catalyzes a light …
Neural timescales reflect behavioral demands in freely moving rhesus macaques
Previous work demonstrated a highly reproducible cortical hierarchy of neural timescales at
rest, with sensory areas displaying fast, and higher-order association areas displaying …
rest, with sensory areas displaying fast, and higher-order association areas displaying …
Combining Designer Receptors Exclusively Activated by Designer Drugs and Resting-State Functional Magnetic Resonance Imaging to Study the Salience Network in …
AK Cushnie - 2023 - search.proquest.com
Abstract The Salience Network (SN) is a large-scale brain network identified originally in
human resting-state functional magnetic resonance imaging (rs-fMRI) studies. Large-scale …
human resting-state functional magnetic resonance imaging (rs-fMRI) studies. Large-scale …