Systematic review of pharmacokinetics and potential pharmacokinetic interactions of flavonolignans from silymarin
V Tvrdý, J Pourová, E Jirkovský, V Křen… - Medicinal Research …, 2021 - Wiley Online Library
Silymarin is an extract from the seeds (fruits) of Silybum marianum that contains
flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its …
flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its …
Development of dual drug loaded nanosized liposomal formulation by a reengineered ethanolic injection method and its pre-clinical pharmacokinetic studies
Oleanolic acid (OA), which is a natural pentacyclic terpenoid, has been identified for hepato-
protective, nephron-protective and cardio-tonic properties. In contrast, doxorubicin (DOX) is …
protective, nephron-protective and cardio-tonic properties. In contrast, doxorubicin (DOX) is …
[PDF][PDF] Anticancerogenic Effects of Silymarin on Diethylnitrosamine-Induced Hepatocellular Carcinoma in Wistar Rats
E Karakurt, S Dağ - Turkish Veterinary Journal, 2020 - dergipark.org.tr
The aim of this study was to evaluate the anticancerogenic effect of Silimarin by
immunohistochemical methods on Diethylnitrosamine (DEN) induced Hepatocellular …
immunohistochemical methods on Diethylnitrosamine (DEN) induced Hepatocellular …
Ratlarda deneysel karaciğer kanser modelinde silymarinin koruyucu etkisinin histopatolojik ve biyokimyasal yöntemlerle araştırılması
E Karakurt - acikbilim.yok.gov.tr
Karaciğer kanseri, dünyada kansere bağlı ölümlerde üçüncü sırada yer almaktadır. HCC,
karaciğerin primer malign tümörlerinin% 70-85'ini oluşturmaktadır. Bu çalışmada ratlarda …
karaciğerin primer malign tümörlerinin% 70-85'ini oluşturmaktadır. Bu çalışmada ratlarda …