In the mammalian brain, cortical interneurons (INs) are a highly diverse group of cells. A key
neurophysiological question concerns how each class of INs contributes to cortical circuit …

The prevalence of autism spectrum disorder (ASD)—a type of neurodevelopmental disorder—
is increasing and is around 2% in North America, Asia, and Europe. Besides the known …

Despite much progress in identifying risk genes for polygenic brain disorders, their core
pathogenic mechanisms remain poorly understood. In particular, functions of many proteins …

Background Children born extremely preterm are at heightened risk for intellectual and
social impairment, including Autism Spectrum Disorder (ASD). There is increasing evidence …

Social isolation is a risk factor for multiple mood disorders. Specifically, social isolation can
remodel the brain, causing behavioral abnormalities, including sociability impairments …

Autism spectrum disorder (ASD) is a series of highly inherited neurodevelopmental
disorders. Loss-of-function (LOF) mutations in the CACNA2D3 gene are associated with …

Autism spectrum disorder (ASD), a group of neurodevelopmental disorder diseases, is
characterized by social deficits, communication difficulties, and repetitive behaviors. Sterile …

Mutations in the beta-amyloid protein (APP) cause familial Alzheimer's disease. In hAPP-J20
mice expressing mutant APP, pharmacological inhibition or genetic ablation of the tyrosine …

Subanesthetic doses of ketamine induce schizophrenia-like behaviors in mice including
hyperlocomotion and deficits in working memory and sensorimotor gating. Here, we …

Background This meta-analysis aimed to explore the most robust findings across numerous
existing resting-state functional imaging and voxel-based morphometry (VBM) studies on the …