CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis
Multiple sclerosis (MS) is characterized by heterogeneity in disease course and prediction of
long-term outcome remains a major challenge. Here, we investigate five myeloid markers …
long-term outcome remains a major challenge. Here, we investigate five myeloid markers …
Chemokine-mediated cell migration into the central nervous system in progressive multifocal leukoencephalopathy
M Deffner, T Schneider-Hohendorf… - Cell Reports …, 2024 - cell.com
Progressive multifocal leukoencephalopathy (PML) has been associated with different forms
of immune compromise. This study analyzes the chemokine signals and attracted immune …
of immune compromise. This study analyzes the chemokine signals and attracted immune …
Cryopreservation of cerebrospinal fluid cells preserves the transcriptional landscape for single-cell analysis
Cerebrospinal fluid (CSF) matrix biomarkers have become increasingly valuable surrogate
markers of neuropsychiatric diseases in research and clinical practice. In contrast, CSF cells …
markers of neuropsychiatric diseases in research and clinical practice. In contrast, CSF cells …
[HTML][HTML] Single cell transcriptomics of cerebrospinal fluid cells from patients with recent-onset narcolepsy
A Huth, I Ayoub, L Barateau, LA Gerdes… - Journal of …, 2024 - Elsevier
Narcolepsy is a rare cause of hypersomnolence and may be associated or not with
cataplexy, ie sudden muscle weakness. These forms are designated narcolepsy-type 1 …
cataplexy, ie sudden muscle weakness. These forms are designated narcolepsy-type 1 …
Enhanced cell survival in prepubertal testicular tissue cryopreserved with membrane lipids and antioxidants rich cryopreservation medium
The present study explores the advantages of enriching the freezing medium with
membrane lipids and antioxidants in improving the outcome of prepubertal testicular tissue …
membrane lipids and antioxidants in improving the outcome of prepubertal testicular tissue …
Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM
AH Pearlman, Y Wang, A Kalluri, M Parker, JD Cohen… - medRxiv, 2024 - medrxiv.org
Patients who have radiographically detectable lesions in their brain or other symptoms
compatible with brain tumors pose challenges for diagnosis. The only definitive way to …
compatible with brain tumors pose challenges for diagnosis. The only definitive way to …
Cryopreservation of cerebrospinal fluid cells preserves transcriptomics integrity for single-cell analysis
M Kodali, J Antone, E Alsop, R Jayakumar, K Parikh… - bioRxiv, 2023 - biorxiv.org
Cerebrospinal fluid (CSF) matrix biomarkers have become increasingly valuable surrogate
markers of neuropsychiatric diseases in research and clinical practice. In contrast, CSF cells …
markers of neuropsychiatric diseases in research and clinical practice. In contrast, CSF cells …