Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus that
affects approximately half of patients with diabetes. Current treatment regimens cannot treat …

ABSTRACT Glucagon-like peptide 1 (GLP-1) is a target for treatment of diabetes; however,
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …

Diabetic peripheral neuropathy (DPN) is caused by hyperglycemia, which induces oxidative
stress and inflammatory responses that damage nerve tissue. Excessive generation of …

Inosine is a dietary supplement that is widely used for managing numerous central
neurological disorders. Interestingly, recent experimental investigation of inosine revealed …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

This study aimed to investigate the anti-neuropathic pain activity and its underlying
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …

Background Since many diabetic patients require combination therapy, the use of herbal
remedies with anti-diabetic activity represents a vital option in diabetes mellitus (DM) …

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes
mellitus (DM) and affects over one-third of all patients. Neuropathic pain and nerve …

Diabetic peripheral neuropathy (DPN) represents a severe microvascular condition that
dramatically affects diabetic patients despite adequate glycemic control, resulting in high …

The heterogeneous nature of multiple sclerosis (MS) and the unavailability of treatments
addressing its intricate network and reversing the disease state is yet an area that needs to …