Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Prebiotics are substrates selectively metabolized by hindgut microorganisms conferring
health benefits. Recent studies suggest polyphenols as candidate to prebiotics. Thus, this …

Polyphenols, including phenolics, alkaloids, and terpenes, are secondary metabolites that
are commonly found in fruits, vegetables, and beverages, such as tea, coffee, wine …

Akkermansia muciniphila, a symbiotic bacterium of the mucus layer, can utilize mucin as its
sole carbon, nitrogen, and energy source. As an abundant resident in the intestinal tract of …

Metabolic diseases can change the gut microbiota composition and function, and
pathogenic bacteria contribute to the development of metabolic disorders. Polyphenols may …

Type 2 diabetes mellitus (T2DM) remains one of the most problematic and economic
consumer disorders worldwide, with growing prevalence and incidence. Over the last years …

Overweight and obesity are associated with several cardiometabolic risk factors, including
insulin resistance, type 2 diabetes, low-grade inflammation and liver diseases. The gut …

Accumulating evidence points to Akkermansia muciniphila as a novel candidate to prevent
or treat obesity-related metabolic disorders. We recently observed, in mice and in humans …

Background Obesity is a leading contributor to numerous diseases, such as diabetes
mellitus, cardiovascular diseases, and cancers. Therefore, seeking effective and safe …

Cardiovascular diseases (CVDs) and diabetes are the leading causes of death worldwide,
which underlines the urgent necessity to develop new pharmacotherapies. Cinnamon has …