Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
[HTML][HTML] Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma
Y Cai, S Dodhia, GH Su - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract The phosphoinositide 3-kinase (PI3K) signaling pathway is the most commonly
mutated pathway in head and neck squamous cell carcinoma (HNSCC). There are several …
mutated pathway in head and neck squamous cell carcinoma (HNSCC). There are several …
New therapies in head and neck cancer
RT Santuray, DE Johnson, JR Grandis - Trends in cancer, 2018 - cell.com
Head and neck squamous cell carcinoma (HNSCC) is a common malignancy with high rates
of mortality and morbidity. Beginning with cetuximab, investigators continue to optimize …
of mortality and morbidity. Beginning with cetuximab, investigators continue to optimize …
miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells
M Vahabi, C Pulito, A Sacconi, S Donzelli… - Journal of Experimental …, 2019 - Springer
Background Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cancer
worldwide. They are typically characterized by a high incidence of local recurrence, which is …
worldwide. They are typically characterized by a high incidence of local recurrence, which is …
[HTML][HTML] Dysregulated lncRNA-UCA1 contributes to the progression of gastric cancer through regulation of the PI3K-Akt-mTOR signaling pathway
C Li, G Liang, S Yang, J Sui, W Yao, X Shen, Y Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) has been
recently shown to be dysregulated during disease occurrence and to play an important role …
recently shown to be dysregulated during disease occurrence and to play an important role …
The PI3K/Akt/mTORC signaling axis in head and neck squamous cell carcinoma: Possibilities for therapeutic interventions either as single agents or in combination …
N Akbari Dilmaghani, A Safaroghli‐Azar… - IUBMB …, 2021 - Wiley Online Library
The latest advances in the sequencing methods in head and neck squamous cell carcinoma
(HNSCC) tissues have revolutionized our understanding of the disease by taking off the veil …
(HNSCC) tissues have revolutionized our understanding of the disease by taking off the veil …
[HTML][HTML] Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma
O Leblanc, S Vacher, C Lecerf, E Jeannot… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
Objective: In patients with head and neck squamous cell carcinoma (HNSCC), cetuximab [a
monoclonal antibody targeting epidermal growth factor receptor (EGFR)] has been shown to …
monoclonal antibody targeting epidermal growth factor receptor (EGFR)] has been shown to …
Perspectives of plant natural products in inhibition of cancer invasion and metastasis by regulating multiple signaling pathways
Background: Metastasis is often derived from increased invasion and migration of tumor
cells, and is the most frequent cause of cancer-associated death. Either the prophylactic or …
cells, and is the most frequent cause of cancer-associated death. Either the prophylactic or …
[HTML][HTML] Targeting oncogenic functions of miR-301a in head and neck squamous cell carcinoma by PI3K/PTEN and MEK/ERK pathways
R Granda-Díaz, L Manterola, F Hermida-Prado… - Biomedicine & …, 2023 - Elsevier
Abstract Treatment of head and neck squamous cell carcinomas (HNSCC), the sixth most
frequent cancer worldwide, remains challenging. miRNA dysregulation is closely linked to …
frequent cancer worldwide, remains challenging. miRNA dysregulation is closely linked to …
Data mining on identifying diagnosis and prognosis biomarkers in head and neck squamous carcinoma
G Ju, Z Yao, Y Zhao, X Zhao, F Liu - Scientific Reports, 2023 - nature.com
Head and neck squamous carcinoma (HNSC) induces high cancer-related death worldwide.
The biomarker screening on diagnosis and prognosis is of great importance. This research …
The biomarker screening on diagnosis and prognosis is of great importance. This research …