The epigenetic machinery in the life cycle and pharmacoepigenetics

R Cacabelos, I Tellado, P Cacabelos - Pharmacoepigenetics, 2019 - Elsevier
Epigenetics is a discipline that studies potentially reversible heritable changes in gene
expression with no structural modifications in the DNA sequence. The epigenetic machinery …

Carbocisteine improves histone deacetylase 2 deacetylation activity via regulating sumoylation of histone deacetylase 2 in human tracheobronchial epithelial cells

Y Song, DY Chi, P Yu, JJ Lu, JR Xu, PP Tan… - Frontiers in …, 2019 - frontiersin.org
Histone deacetylase (HDAC) 2 plays a vital role in modifying histones to mediate
inflammatory responses, while HDAC2 itself is commonly regulated by post-translational …