The position of Chlamydomonas within the eukaryotic phylogeny makes it a unique model in
at least two important ways: as a representative of the critically important, early‐diverging …

Centrioles are conserved microtubule-based organelles that lie at the core of the animal
centrosome and play a crucial role in nucleating the formation of cilia and flagella in most …

Mutations in human CEP290 cause cilia-related disorders that range in severity from
isolated blindness to perinatal lethality. Here, we describe a Chlamydomonas reinhardtii …

Centrin has been shown to be involved in centrosome biogenesis in a variety of eukaryotes.
In this study, we characterize hPOC5, a conserved centrin-binding protein that contains …

Basal bodies and centrioles play central roles in microtubule (MT)‐organizing centres within
many eukaryotes. They share a barrel‐shaped cylindrical structure composed of nine MT …

Centriole duplication begins with the formation of a single procentriole next to a preexisting
centriole. CPAP (centrosomal protein 4.1–associated protein) was previously reported to …

Basal bodies are modified centrioles that give rise to cilia and flagella. The basal body is a
complex structure that can form through at least two distinct pathways depending on the cell …

In unicellular and multicellular eukaryotes, fast cell motility and rapid movement of material
over cell surfaces are often mediated by ciliary or flagellar beating. The conserved defining …

ABSTRACT The protein nephrocystin-4 (NPHP4) is widespread in ciliated organisms, and
defects in NPHP4 cause nephronophthisis and blindness in humans. To learn more about …

Centrioles form the core of the centrosome in animal cells and function as basal bodies that
nucleate and anchor cilia at the plasma membrane. In this paper, we report that Cep120 …