LncRNAs in cancer: regulatory and therapeutic implications

A Nandwani, S Rathore, M Datta - Cancer letters, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) comprise a class of RNAs that do not code for proteins but
are critical in regulating diverse cellular processes and maintaining cell function. In doing so …

Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy

H Shaath, R Vishnubalaji, R Elango, S Khattak… - Cell Death …, 2021 - nature.com
Cumulative evidence suggests added benefit for neoadjuvant chemotherapy (NAC) in a
subset of triple-negative breast cancer (TNBC) patients. Herein we identified the long …

An overview of long non-coding (lnc) RNAs in neuroblastoma

F Baldini, M Calderoni, L Vergani, P Modesto… - International journal of …, 2021 - mdpi.com
Neuroblastoma (NB) is a heterogeneous developmental tumor occurring in childhood, which
arises from the embryonic sympathoadrenal cells of the neural crest. Although the recent …

Hypoxia-sensitive long noncoding RNA CASC15 promotes lung tumorigenesis by regulating the SOX4/β-catenin axis

J Sun, Y Xiong, K Jiang, B Xin, T Jiang, R Wei… - Journal of Experimental …, 2021 - Springer
Background Accumulating evidence has demonstrated that long non-coding RNAs
(lncRNAs) are involved in the hypoxia-related cancer process and play pivotal roles in …

Linc00839 promotes neuroblastoma progression by sponging mir-454-3p to up-regulate Neurod1

Q Zhang, J Wei, N Li, B Liu - Neurochemical research, 2022 - Springer
Neuroblastoma (NB) is the most common extracranial solid malignancy in children.
Increasing long non-coding RNAs (lncRNAs) are reported to be associated with NB …

Adipose-derived stem cell-derived extracellular vesicles inhibit neuroblastoma growth by regulating GABBR1 activity through LINC00622-mediated transcription factor …

M Guo, D Li, Y Feng, M Li, B Yang - Journal of Leukocyte …, 2022 - academic.oup.com
Neuroblastoma (NB) is a huge threat to children's health. Adipose-derived stem cells-
derived extracellular vesicles (ADSC-Evs) can regulate tumor progression. This study aimed …

LINC00839 regulates proliferation, migration, invasion, apoptosis and glycolysis in neuroblastoma cells through miR-338-3p/GLUT1 axis

L Yang, L Pei, J Yi - Neuropsychiatric disease and treatment, 2021 - Taylor & Francis
Background Long noncoding RNAs (lncRNAs) are related to the development and treatment
of neuroblastoma. The lncRNA LINC00839 is dysregulated in neuroblastoma, while its …

Targeting neuroblastoma by small-molecule inhibitors of human ALYREF protein: mechanistic insights using molecular dynamics simulations

N Goswami, A Singh, S Bharadwaj… - Journal of …, 2023 - Taylor & Francis
Neuroblastoma is a tumour of the sympathetic nervous system mainly prevalent in children.
Many strategies have been employed to target several drug-targetable proteins for the …

[HTML][HTML] Role of mammalian long non-coding RNAs in normal and neuro oncological disorders

N Singh - Genomics, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) are expressed at lower levels than protein-coding genes
but have a crucial role in gene regulation. LncRNA is distinct, they are being transcribed …

A novel ferroptosis-related lncRNA prognostic model and immune infiltration features in skin cutaneous melanoma

S Sun, G Zhang, L Zhang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Background: Skin cutaneous melanoma (SKCM) is an aggressive malignant skin tumor.
Ferroptosis is an iron-dependent cell death that may mobilize tumor-infiltrating immunity …