Infections, vaccines and autoimmunity: a multiple sclerosis perspective

D Jakimovski, B Weinstock-Guttman, M Ramanathan… - Vaccines, 2020 - mdpi.com
Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative
disease that is associated with multiple environmental factors. Among suspected …

Vascular aspects of multiple sclerosis: emphasis on perfusion and cardiovascular comorbidities

D Jakimovski, M Topolski, AV Genovese… - Expert review of …, 2019 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and
neurodegenerative disease of the central nervous system. Over the last two decades, more …

Serum neurofilament light chain level associations with clinical and cognitive performance in multiple sclerosis: A longitudinal retrospective 5-year study

D Jakimovski, R Zivadinov… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: A limited number of studies investigated associations between serum
neurofilament light chain (sNfL) and cognition in persons with multiple sclerosis (PwMS) …

Serum neurofilament light chain levels associations with gray matter pathology: a 5‐year longitudinal study

D Jakimovski, J Kuhle, M Ramanathan… - Annals of clinical …, 2019 - Wiley Online Library
Background Gray matter (GM) pathology is closely associated with physical and cognitive
impairment in persons with multiple sclerosis (PwMS). Similarly, serum neurofilament light …

Cognitive profiles of aging in multiple sclerosis

D Jakimovski, B Weinstock-Guttman, S Roy… - Frontiers in aging …, 2019 - frontiersin.org
Background Increasingly favorable mortality prognosis in multiple sclerosis (MS) raises
questions regarding MS-specific cognitive aging and the presence of comorbidities such as …

Thalamic nuclei volumes and their relationships to neuroperformance in multiple sclerosis: a cross‐sectional structural MRI study

N Bergsland, RHB Benedict, MG Dwyer… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Although reduced thalamic volume is associated with multiple sclerosis (MS)‐
related clinical impairment, the role of individual thalamic nuclei remains poorly understood …

Multimodal-neuroimaging machine-learning analysis of motor disability in multiple sclerosis

B Rehák Bučková, J Mareš, A Škoch, J Kopal… - Brain Imaging and …, 2023 - Springer
Motor disability is a dominant and restricting symptom in multiple sclerosis, yet its
neuroimaging correlates are not fully understood. We apply statistical and machine learning …

Proteomics and relationship with axonal pathology in multiple sclerosis: 5-year diffusion tensor imaging study

D Jakimovski, F Qureshi, M Ramanathan… - Brain …, 2023 - academic.oup.com
Blood-based biomarkers can be economic and easily accessible tools for monitoring and
predicting disease activity in multiple sclerosis. The objective of this study was to determine …

Axonal loss in major sensorimotor tracts is associated with impaired motor performance in minimally disabled multiple sclerosis patients

M Strik, LE Cofré Lizama, CJ Shanahan… - Brain …, 2021 - academic.oup.com
Multiple sclerosis is a neuroinflammatory disease of the CNS that is associated with
significant irreversible neuro-axonal loss, leading to permanent disability. There is thus an …

Neural correlates of digital measures shown by structural MRI: a post-hoc analysis of a smartphone-based remote assessment feasibility study in multiple sclerosis

M Ganzetti, JS Graves, SP Holm, F Dondelinger… - Journal of …, 2023 - Springer
Background A study was undertaken to evaluate remote monitoring via smartphone sensor-
based tests in people with multiple sclerosis (PwMS). This analysis aimed to explore …