Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

Since the identification and characterization of gasdermin (GSDM) D as the main effector of
inflammatory regulated cell death (or pyroptosis), literature on the GSDM family of pore …

The fourth common reason of death among patients is gastric cancer (GC) and it is a
dominant tumor type in Ease Asia. One of the problems in GC therapy is chemoresistance …

Pyroptosis is a novel regulated cell death (RCD) mode associated with inflammation and
innate immunity. Gasdermin E (GSDME), a crucial component of the gasdermin (GSDM) …

Pancreatic cancer is difficult to resect due to its unique challenges, often leading to
incomplete tumor resections. Fluorescence-guided surgery (FGS), also known as …

Background Tumor cells can resist chemotherapy-induced pyroptosis through glycolytic
reprogramming. Estrogen-related receptor alpha (ERRα) is a central regulator of cellular …

Abstract The PI3K/AKT/mTOR signaling pathway is one of the most common abnormal
activation pathways in tumor cells, and has associated with multiple functions such as tumor …

The field of ferroptosis research has grown exponentially since this form of cell death was
first identified over a decade ago. Ferroptosis, an iron-and ROS-dependent type of cell …

Nonprogrammed cell death (NPCD) and programmed cell death (PCD) are two types of cell
death. Cell death is significantly linked to tumor development, medication resistance, cancer …

Highlights What are the main findings? Mucus, as the most widely distributed biofilm and
vital protective barrier on the surface of mucous membranes throughout the body, fulfills a …