Inhaled Pollutants of the Gero-Exposome and Later-Life Health
CE Finch, MA Thorwald - The Journals of Gerontology: Series A, 2024 - academic.oup.com
Inhaled air pollutants (AirP) comprise extraordinarily diverse particles, volatiles, and gases
from traffic, wildfire, cigarette smoke, dust, and various other sources. These pollutants …
from traffic, wildfire, cigarette smoke, dust, and various other sources. These pollutants …
Air pollution particulate matter amplifies white matter vascular pathology and demyelination caused by hypoperfusion
MT Huuskonen, Q Liu, K Lamorie-Foote… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular pathologies are commonly associated with dementia. Because air pollution
increases arterial disease in humans and rodent models, we hypothesized that air pollution …
increases arterial disease in humans and rodent models, we hypothesized that air pollution …
Iron Overload in Brain: Transport Mismatches, Microbleeding Events, and How Nanochelating Therapies May Counteract Their Effects
E Ficiarà, I Stura, A Vernone, F Silvagno… - International Journal of …, 2024 - mdpi.com
Iron overload in many brain regions is a common feature of aging and most
neurodegenerative diseases. In this review, the causes, mechanisms, mathematical models …
neurodegenerative diseases. In this review, the causes, mechanisms, mathematical models …
Air pollution, dementia, and lifespan in the socio-economic gradient of aging: perspective on human aging for planning future experimental studies
CE Finch - Frontiers in Aging, 2023 - frontiersin.org
Air pollution (AirPoll) accelerates human aging, as assessed by increased adult mortality
and earlier onset of cardiovascular diseases, and dementia. Socio-economic strata (SES) of …
and earlier onset of cardiovascular diseases, and dementia. Socio-economic strata (SES) of …
Neurotoxicity of diesel exhaust particles
K Shkirkova, K Lamorie-Foote, N Zhang… - Journal of …, 2022 - content.iospress.com
Background: Air pollution particulate matter (PM) is strongly associated with risks of
accelerated cognitive decline, dementia and Alzheimer's disease. Ambient PM batches have …
accelerated cognitive decline, dementia and Alzheimer's disease. Ambient PM batches have …
Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice
K Lamorie‐Foote, Q Liu, K Shkirkova… - Journal of …, 2023 - Wiley Online Library
Chronic cerebral hypoperfusion (CCH) may amplify the neurotoxicity of nanoscale
particulate matter (nPM), resulting in white matter injury. This study characterized the joint …
particulate matter (nPM), resulting in white matter injury. This study characterized the joint …
Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity
H Zhang, C d'Agostino, C Tulisiak, MA Thorwald… - Heliyon, 2023 - cell.com
Background Epidemiological studies have variably linked air pollution to increased risk of
Parkinson's disease (PD). However, there is little experimental evidence for this association …
Parkinson's disease (PD). However, there is little experimental evidence for this association …
[HTML][HTML] Magnetic resonance imaging of white matter response to diesel exhaust particles
A Chakhoyan, K Shkrkova, S Sizdahkhani… - Research …, 2023 - ncbi.nlm.nih.gov
Air pollution is associated with risks of dementia and accelerated cognitive decline. Rodent
air pollution models have shown white matter vulnerability. This study uses diffusion tensor …
air pollution models have shown white matter vulnerability. This study uses diffusion tensor …
[PDF][PDF] Recently decreased association of air pollution with cognitive impairment in a population-based aging cohort and in a mouse model
JA Ailshire, CE Finch - Alzheimers Dement., 2022 - gero.usc.edu
3. Gatto NM, Henderson VW, Hodis HN, et al. Components of air pollution and cognitive
function in middle-aged and older adults in Los Angeles. NeuroToxicology. 2014; 40: 1-7. 4 …
function in middle-aged and older adults in Los Angeles. NeuroToxicology. 2014; 40: 1-7. 4 …