Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is featured by intensive
inflammatory responses and oxidative stress, which lead to cytokine storms and pyroptosis …

Bronchopulmonary dysplasia (BPD) is one of the major causes of chronic respiratory
diseases among infants. Both pharmacological and nonpharmacological approaches have …

Intra-amniotic infection (IAI) is one major driver for preterm birth and has been demonstrated
by clinical studies to exert both beneficial and injurious effects on the premature lung …

Background Gut microbiota colonization is critical for immune education and nutrient
metabolism. Research shows that melatonin has beneficial effects as a therapy for many …

Hepatitis is a major public health problem that increases the risk of liver cirrhosis and liver
cancer. Numerous studies have revealed that long non-coding RNAs (lncRNAs) exert …

Prenatal exposure to air pollution may associated with inhibition of lung development in the
child, however the possible mechanism is unclear. We investigated the effects of traffic …

Intrauterine inflammation is shown to be associated with preterm birth, fetal inflammatory
response syndrome, and other pregnancy‐related comorbidities such as central nervous …

Melatonin is a phylogenetically ancient molecule with diverse biological activities, including
anti-inflammatory and redox properties. Although its role as an antioxidant is well …

For preterm infants, bronchopulmonary dysplasia (BPD) is usually caused by abnormal lung
development due to various factors during prenatal and postnatal process. One of the …

In the setting of threatened extreme preterm birth, balancing maternal and fetal risks and
benefits in order to choose the best available treatment options is of utmost importance …